Aspartic Acid

granzyme B ; Homo sapiens







24 Article(s)
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Pub. Year
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1 27152961 Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution. 2016 2
2 25489668 A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl. 2014 Nov 28 1
3 25490769 Dynamic conformations of nucleophosmin (NPM1) at a key monomer-monomer interface affect oligomer stability and interactions with granzyme B. 2014 1
4 21548883 Cleavage of Notch1 by granzyme B disables its transcriptional activity. 2011 Jul 15 1
5 16870146 The MPAC domain is a novel mitotically regulated domain, removed by apoptotic protease cleavage during cell death. 2006 Sep 8 1
6 15713684 Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis. 2005 Apr 22 1
7 15980455 GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences. 2005 Jul 1 1
8 15117953 Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens. 2004 Jul 2 1
9 11802788 The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis. 2002 Feb 1 1
10 12208735 Granzyme B-mediated degradation of T-cell receptor zeta chain. 2002 Sep 1 1
11 11278311 Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop. 2001 May 4 2
12 11325591 The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1. 2001 Apr 4
13 11420045 Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death. 2001 Jun 1
14 10708865 Caspases - controlling intracellular signals by protease zymogen activation. 2000 Mar 7 1
15 10966646 The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity. 2000 Sep 1
16 11209755 Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue. 2000 Dec 2
17 9774654 Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. 1998 Nov 2
18 8665848 The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. 1996 May 15 1
19 8805307 Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3. 1996 Jul 1 1
20 17180094 The ICE family of cysteine proteases as effectors of cell death. 1996 Jul 1
21 7722467 Granzyme A is an interleukin 1 beta-converting enzyme. 1995 May 1 1
22 8034581 Granule serine proteases are normal nuclear constituents of natural killer cells. 1994 Jul 15 1
23 8251751 Rapid purification of cationic granule proteases: application to human granzymes. 1993 Oct 1
24 1985927 Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity. 1991 Jan 5 1