Title : Cleavage of Notch1 by granzyme B disables its transcriptional activity.

Pub. Date : 2011 Jul 15

PMID : 21548883






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We demonstrate that GrB cleaved the intracellular Notch1 domain at least twice at two distinct aspartic acids, Asp1860 and Asp1961. Aspartic Acid granzyme B Homo sapiens