Phenobarbital

cytochrome P450 2B1 ; Rattus norvegicus







31 Article(s)
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1 25710017 Ring-oxidative biotransformation and drug interactions of propofol in the livers of rats. 2015 1
2 19427778 Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway. 2010 Apr 7
3 18803253 Docosahexaenoic acid downregulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the c-Jun NH2-terminal kinase mitogen-activated protein kinase pathway. 2009 Mar 6
4 17904175 DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation. 2007 Dec 15 1
5 16154717 Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes. 2006 Feb 8 2
6 16517146 n-6 and n-3 polyunsaturated fatty acids down-regulate cytochrome P-450 2B1 gene expression induced by phenobarbital in primary rat hepatocytes. 2006 Oct 9
7 15629132 Prostaglandin E2 down-regulation of cytochrome P-450 2B1 expression induced by phenobarbital is through EP2 receptor in rat hepatocytes. 2005 Feb 11 4
8 14722249 Transcriptional regulation of CYP2B1 induction in primary rat hepatocyte cultures: repression by epidermal growth factor is mediated via a distal enhancer region. 2004 Jan 4
9 15208357 Microdissected region-specific gene expression analysis with methacarn-fixed, paraffin-embedded tissues by real-time RT-PCR. 2004 Jul 1
10 11377398 Induction of cytochrome P450 2B1 by pyrethroids in primary rat hepatocyte cultures. 2001 Jul 1 2
11 12094624 Prostaglandin E2 is involved in the increase of cytochrome P-450 2B1 expression by alpha-tocopheryl succinate in primary rat hepatocytes in the presence of phenobarbital. 2001 5
12 10773077 Functional interactions between an atypical NF-kappaB site from the rat CYP2B1 promoter and the transcriptional repressor RBP-Jkappa/CBF1. 2000 May 15 1
13 10781875 Induction of cytochrome P450 2B1-mRNA and pentoxyresorufin O-depentylation after exposure of precision-cut rat liver slices to phenobarbital. 2000 Apr 3 1
14 10871056 Mechanistic studies of cytochrome P450 2B1 inactivation by xanthates. 2000 Jun 1 1
15 10205668 CYP2B2 gene expression and phenobarbital induction in kidneys using an in vitro transcription system. 1999 Feb 1
16 10205826 [Interstrain differences in enzymatic activity of CYP2B1 and expression of its gene in the rat liver during induction with phenobarbital and triphenyldioxane]. 1999 Jan-Feb 1
17 10385683 Mimicry in primary rat hepatocyte cultures of the in vivo perivenous induction by phenobarbital of cytochrome P-450 2B1 mRNA: role of epidermal growth factor and perivenous oxygen tension. 1999 Jul 1
18 10423399 Cis-acting sequences from the rat cytochrome P450 2B1 gene confer pulmonary and phenobarbital-inducible expression in transgenic mice. 1999 Aug 2
19 10547882 [Change in the rat liver microsomal monooxygenase system upon induction with phenobarbital in acute pancreatitis]. 1999 Jul-Aug 2
20 9763409 Catalytic properties of an expressed cytochrome P450 2B1 from a Wistar-Kyoto rat liver cDNA library. 1998 Oct 1
21 9101035 Chlorodibromomethane metabolism to bromide and carbon monoxide in rats. 1997 2
22 9111218 Alkylation of cellular macromolecules and target specificity of carcinogenic nitrosodialkylamines: metabolic activation by cytochromes P450 2B1 and 2E1. 1997 Apr 2
23 9168259 Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1-aminobenzotriazole. 1997 May 1
24 9347925 Lack of correlation between hepatic prostaglandin concentrations and DNA synthesis after the administration of phenobarbital and the peroxisome proliferator ciprofibrate in rats. 1997 Nov 21 1
25 8573202 Transcriptional regulation of the CYP2B1 and CYP2B2 genes by C/EBP-related proteins. 1996 Feb 9 2
26 8625499 Identification of the cytochrome P450 isozymes involved in the metabolism of N-nitrosodipropyl-,N-nitrosodibutyl- and N-nitroso-n-butyl-n-propylamine. 1996 Apr 1
27 7607552 Localization of a phenobarbital-responsive element (PBRE) in the 5'-flanking region of the rat CYP2B2 gene. 1995 Jun 9 2
28 8558843 Critical role of extracellular matrix on induction by phenobarbital of cytochrome P450 2B1/2 in primary cultures of adult rat hepatocytes. 1995 Dec 1
29 7513451 Regulation of cytochrome P450 2B1/2 mRNAs by Kepone (chlordecone) and potent estrogens in primary cultures of adult rat hepatocytes on Matrigel. 1994 Apr 2
30 8274163 Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate. 1993 Dec 14 2
31 8382483 Regulation of fibronectin mRNA expression in primary hepatocytes in response to EGF and phenobarbital. 1993 Feb 15 5