NAD

poly (ADP-ribose) polymerase 1 ; Rattus norvegicus







74 Article(s)
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1 34789130 Model of Streptozotocin-Nicotinamide Induced Type 2 Diabetes: A Comparative Review. 2021 Nov 17 2
2 32380185 Nicotinamide mononucleotide administration after sever hypoglycemia improves neuronal survival and cognitive function in rats. 2020 Jul 1
3 33041769 Mechanism of Zinc Excitotoxicity: A Focus on AMPK. 2020 1
4 33425964 Ozone Exposure Induces Metabolic Disorders and NAD+ Depletion Through PARP1 Activation in Spinal Cord Neurons. 2020 3
5 31590397 Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells. 2019 Oct 5 3
6 28844085 Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors: a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia? 2018 Feb 1
7 30214397 Ketogenic Diet Modulates NAD+-Dependent Enzymes and Reduces DNA Damage in Hippocampus. 2018 2
8 28130107 Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo. 2017 Mar 4 1
9 27686254 The poly(ADP-ribosyl)ation of FoxO3 mediated by PARP1 participates in isoproterenol-induced cardiac hypertrophy. 2016 Dec 1
10 25287541 Short- and long-term consequences of perinatal asphyxia: looking for neuroprotective strategies. 2015 4
11 25341378 Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation. 2015 Apr 1
12 25835215 Perinatal asphyxia leads to PARP-1 overactivity, p65 translocation, IL-1β and TNF-α overexpression, and apoptotic-like cell death in mesencephalon of neonatal rats: prevention by systemic neonatal nicotinamide administration. 2015 May 1
13 25868125 Chromosomal damage and micronucleus induction by MP-124, a novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor: Evidence for a non-DNA-reactive mode of action. 2015 Apr 4
14 25934569 PJ-34 inhibits PARP-1 expression and ERK phosphorylation in glioma-conditioned brain microvascular endothelial cells. 2015 Aug 15 2
15 26218637 Salvage of nicotinamide adenine dinucleotide plays a critical role in the bioenergetic recovery of post-hypoxic cardiomyocytes. 2015 Oct 1
16 26462257 Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. 2015 1
17 24231740 Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation. 2014 Jan 31 1
18 24337988 Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence. 2014 Apr 2
19 24586272 Neurological and histological consequences induced by in vivo cerebral oxidative stress: evidence for beneficial effects of SRT1720, a sirtuin 1 activator, and sirtuin 1-mediated neuroprotective effects of poly(ADP-ribose) polymerase inhibition. 2014 2
20 24723845 Perinatal asphyxia: CNS development and deficits with delayed onset. 2014 2
21 24842055 Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes. 2014 Jul 31 4
22 23846805 Continuous inhibition of poly(ADP-ribose) polymerase does not reduce reperfusion injury in isolated rat heart. 2013 Jul 1
23 24278448 Pyruvate administration reduces recurrent/moderate hypoglycemia-induced cortical neuron death in diabetic rats. 2013 1
24 22311271 Further studies on the hypothesis of PARP-1 inhibition as a strategy for lessening the long-term effects produced by perinatal asphyxia: effects of nicotinamide and theophylline on PARP-1 activity in brain and peripheral tissue : nicotinamide and theophylline on PARP-1 activity. 2012 Jul 2
25 22339640 Increased PARP-1 levels in nuclear matrix isolated from heat shock treated rat liver. 2012 Jan 2
26 22352983 Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide. 2012 May 1 4
27 21399558 Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis. 2011 Jul 5
28 21416227 PARP inhibition prevents oxidative injury of bladder induced by acute urinary retention and subsequent emptying. 2011 Jun 1
29 21541336 Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. 2011 Apr 26 6
30 20122899 Automodification of PARP-1 mediates its tight binding to the nuclear matrix. 2010 Feb 26 2
31 20132901 PISA, a novel pharmacodynamic assay for assessing poly(ADP-ribose) polymerase (PARP) activity in situ. 2010 May-Jun 3
32 19178345 Determination of NAD(+) and NADH in a single cell under hydrogen peroxide stress by capillary electrophoresis. 2009 Feb 1 2
33 19513971 Roles of inhibitors of poly(ADP-ribose) polymerase in protecting rat RINm5F cell line against free fatty acid-induced apoptosis. 2009 Jun 2
34 16736046 Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. 2007 Feb 2
35 17127275 Intranasal administration with NAD+ profoundly decreases brain injury in a rat model of transient focal ischemia. 2007 Jan 1 5
36 17766683 Differential contribution of poly(ADP-ribose)polymerase-1 and -2 (PARP-1 and -2) to the poly(ADP-ribosyl)ation reaction in rat primary spermatocytes. 2007 Nov 1
37 15466246 A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. 2005 Feb 1
38 16181422 Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. 2005 Oct 1
39 14754756 Ontogeny of poly(ADP-ribose) polymerase-1 in lung and developmental implications. 2004 Jun 2
40 15075382 A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia. 2004 Aug 3
41 15111611 Protection by pyruvate of rat retinal cells against zinc toxicity in vitro, and pressure-induced ischemia in vivo. 2004 May 4
42 15147502 Acute ammonia intoxication induces an NMDA receptor-mediated increase in poly(ADP-ribose) polymerase level and NAD metabolism in nuclei of rat brain cells. 2004 Jun 2
43 15207836 Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy. 2004 Jul-Aug 4
44 15465278 Neuronal trauma model: in search of Thanatos. 2004 Nov 1
45 12824290 Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation. 2003 Aug 1
46 12834903 Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat. 2003 Jul 18 4
47 15206738 Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells. 2003 3
48 15206786 NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators. 2003 1
49 11999706 Poly(ADP-ribose) polymerase activation and cell injury in the course of rat heart heterotopic transplantation. 2002 Jan 1
50 12379464 Niacin deficiency increases spontaneous and etoposide-induced chromosomal instability in rat bone marrow cells in vivo. 2002 Oct 31 2