Title : Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.

Pub. Date : 2003 Aug

PMID : 12824290






1 Functional Relationships(s)
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1 We hypothesize that poly (ADP-ribosyl)ation, that is, poly (ADP-ribose) polymerase (PARP)-dependent transfer of ADP-ribose moieties from NAD to nuclear proteins, plays a role in diabetic nephropathy. NAD poly (ADP-ribose) polymerase 1 Rattus norvegicus