Serine

protein kinase C alpha ; Homo sapiens







90 Article(s)
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1 35102644 Protein kinase Cα activation switches YAP1 from TEAD-mediated signaling to p73-mediated signaling. 2022 Apr 1
2 35451598 Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria. 2022 May 2
3 33307285 The complexities of PKCα signaling in cancer. 2021 May 3
4 34682865 Diosmetin Induces Modulation of Igf-1 and Il-6 Levels to Alter Rictor-Akt-PKCα Cascade in Inhibition of Prostate Cancer. 2021 Oct 15 2
5 34944403 The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the Angiogenesis Induced by the Pancreatic Cancer Derived EVs. 2021 Nov 24 2
6 31801866 PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly. 2020 Feb 14 3
7 30733340 Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it. 2019 Mar 29 3
8 31177095 Trophoblast cell surface antigen 2 (Trop-2) phosphorylation by protein kinase C α/δ (PKCα/δ) enhances cell motility. 2019 Jul 26 1
9 29889984 VCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions. 2018 Jul 1
10 28331048 G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of β-Arrestin. 2017 Jun 1
11 29383184 Stabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells. 2017 Dec 29 1
12 26703243 Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2. 2016 Feb 3
13 25954875 PKCα-Mediated Signals Regulate the Motile Responses of Cochlear Outer Hair Cells. 2015 May 5 3
14 26160374 Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKCα Activity under Mechanical Stimulation on the Elastomeric Substrates. 2015 1
15 24225947 Protein phosphatase 2A is regulated by protein kinase Cα (PKCα)-dependent phosphorylation of its targeting subunit B56α at Ser41. 2014 Jan 3 1
16 24519946 Isoform-specific and protein kinase C-mediated regulation of CTP:phosphoethanolamine cytidylyltransferase phosphorylation. 2014 Mar 28 1
17 25086031 Phosphorylation of Cdc42 effector protein-4 (CEP4) by protein kinase C promotes motility of human breast cells. 2014 Sep 12 5
18 23275623 Regulation of interleukin-6 secretion by the two-pore-domain potassium channel Trek-1 in alveolar epithelial cells. 2013 Feb 15 1
19 23290264 Apelin-13 increases expression of ATP-binding cassette transporter A1 via activating protein kinase C α signaling in THP-1 macrophage-derived foam cells. 2013 Feb 1
20 23413252 Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle. 2013 Apr 15 1
21 23470774 Surgical incision induces phosphorylation of AMPA receptor GluR1 subunits at Serine-831 sites and GluR1 trafficking in spinal cord dorsal horn via a protein kinase Cγ-dependent mechanism. 2013 Jun 14 2
22 23979140 Regulated norepinephrine transporter interaction with the neurokinin-1 receptor establishes transporter subcellular localization. 2013 Oct 4 1
23 22049330 A late phase of LTD in cultured cerebellar Purkinje cells requires persistent dynamin-mediated endocytosis. 2012 Jan 1
24 22730012 PKC activation is required for TSH-mediated lipolysis via perilipin activation. 2012 Oct 1
25 22918940 Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism. 2012 Oct 2
26 23115237 The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition. 2012 Dec 21 2
27 21156788 Ca2+/calmodulin-dependent protein kinase II inhibitors disrupt AKAP79-dependent PKC signaling to GluA1 AMPA receptors. 2011 Feb 25 1
28 21251911 Acidic extracellular pH induces p120-catenin-mediated disruption of adherens junctions via the Src kinase-PKCδ pathway. 2011 Feb 18 1
29 21349850 MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation. 2011 Apr 29 1
30 21705328 Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively. 2011 Aug 26 2
31 19464346 Participation of signaling pathways in the derepression of luteinizing hormone receptor transcription. 2010 Jan 27 1
32 19966277 Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. 2010 Mar 2
33 20122401 RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer. 2010 Jan 29 1
34 20348139 Translocation of protein kinase C isoforms is involved in propofol-induced endothelial nitric oxide synthase activation. 2010 May 1
35 20472934 Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. 2010 Jul 23 1
36 20654585 Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells. 2010 Nov 1 2
37 20691662 TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha. 2010 Sep 10 2
38 20844753 Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability. 2010 Sep 10 1
39 20861471 Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells. 2010 Dec 1
40 21106840 EphrinBs regulate D-serine synthesis and release in astrocytes. 2010 Nov 24 1
41 18950621 PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway. 2009 Jan 1 1
42 19231233 Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNgamma. 2009 Apr 1
43 19318349 Phosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1. 2009 Jun 5 3
44 19459855 Protein kinase Calpha-responsive polymeric carrier: its application for gene delivery into human cancers. 2009 Aug 1
45 19581409 Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. 2009 Jul 13 1
46 19672862 Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis. 2009 Dec 1 1
47 18372343 Protein kinase Calpha-induced derepression of the human luteinizing hormone receptor gene transcription through ERK-mediated release of HDAC1/Sin3A repressor complex from Sp1 sites. 2008 Jun 4
48 18412141 Epstein-Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI-PLC-PKCalpha/PKCbeta pathway. 2008 Dec 1
49 18991684 Post-transcriptional regulation of HSP70 expression following oxidative stress in SH-SY5Y cells: the potential involvement of the RNA-binding protein HuR. 2008 1
50 20592962 Regulation of Transgene Expression in Tumor Cells by Exploiting Endogenous Intracellular Signals. 2008 Dec 17 2