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31426858 | Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells. | 2019 Aug 19 |
2 |
| 2 |
28731171 | Protective role of Pollen Typhae total flavone against the palmitic acid-induced impairment of glucose-stimulated insulin secretion involving GPR40 signaling in INS-1 cells. | 2017 Sep |
2 |
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24666736 | CNX-011-67, a novel GPR40 agonist, enhances glucose responsiveness, insulin secretion and islet insulin content in n-STZ rats and in islets from type 2 diabetic patients. | 2014 Mar 25 |
1 |
| 4 |
23911664 | GPR40 protein levels are crucial to the regulation of stimulated hormone secretion in pancreatic islets. Lessons from spontaneous obesity-prone and non-obese type 2 diabetes in rats. | 2013 Dec 5 |
1 |
| 5 |
22332921 | Long-term in vitro treatment of INS-1 rat pancreatic β-cells by unsaturated free fatty acids protects cells against gluco- and lipotoxicities via activation of GPR40 receptors. | 2012 May |
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| 6 |
21319751 | Design, synthesis, and biological activity of potent and orally available G protein-coupled receptor 40 agonists. | 2011 Mar 10 |
3 |
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21752941 | TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats. | 2011 Oct |
1 |
| 8 |
20888730 | DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats. | 2010 Nov |
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| 9 |
24900210 | Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist. | 2010 Sep 9 |
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| 10 |
19217448 | Acute administration of GPR40 receptor agonist potentiates glucose-stimulated insulin secretion in vivo in the rat. | 2009 Mar |
1 |
| 11 |
17101212 | Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40. | 2007 Jan 15 |
5 |
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16214394 | GPR40, a free fatty acid receptor on pancreatic beta cells, regulates insulin secretion. | 2005 Oct |
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