2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 25801005 Influence of HIV antiretrovirals on methadone N-demethylation and transport. 2015 May 15 2
2 25217544 Fatal methadone toxicity: potential role of CYP3A4 genetic polymorphism. 2014 Oct 1
3 22511698 Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients. 2012 May 1
4 20825389 Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation. 2011 Jan 1
5 17598095 An in vitro approach to potential methadone metabolic-inhibition interactions. 2007 Sep 1
6 14628297 Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19. 2004 Jan 1
7 15371986 Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone. 2004 Sep 1
8 15501692 Methadone--metabolism, pharmacokinetics and interactions. 2004 Dec 2
9 11318772 A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio. 2001 Apr 3
10 11504799 Metabolism of methadone and levo-alpha-acetylmethadol (LAAM) by human intestinal cytochrome P450 3A4 (CYP3A4): potential contribution of intestinal metabolism to presystemic clearance and bioactivation. 2001 Sep 2
11 11069437 Steady-state pharmacokinetics of (R)- and (S)-methadone in methadone maintenance patients. 2000 Nov 1
12 10233205 Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4. 1999 Apr 2