tofacitinib

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







10 Article(s)
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Pub. Year
#Total Relationships
1 35139477 Synthesis and evaluation of tofacitinib analogs designed to mitigate metabolic activation. 2022 Apr 2
2 34069798 Pharmacokinetic Drug Interaction between Tofacitinib and Voriconazole in Rats. 2021 May 18 1
3 31833760 "Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4": Revisiting the Significance of the Epoxide Intermediate and Glutathione Trapping. 2020 Feb 17 7
4 32367507 Critical Assessment of Pharmacokinetic Drug-Drug Interaction Potential of Tofacitinib, Baricitinib and Upadacitinib, the Three Approved Janus Kinase Inhibitors for Rheumatoid Arthritis Treatment. 2020 Aug 1
5 32469513 Reply to Letter to Editor from Veeravalli and Dash on "Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4: Revisiting the Significance of the Epoxide Intermediate and Glutathione Trapping". 2020 Jul 20 1
6 31414593 Tofacitinib Is a Mechanism-Based Inactivator of Cytochrome P450 3A4. 2019 Sep 16 1
7 27138968 Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers. 2016 Sep 1
8 24464803 The pharmacokinetics, metabolism, and clearance mechanisms of tofacitinib, a janus kinase inhibitor, in humans. 2014 Apr 1
9 27128233 Evaluation of the effect of fluconazole and ketoconazole on the pharmacokinetics of tofacitinib in healthy adult subjects. 2014 Jan 2
10 22233204 Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data. 2012 Jul 4