Methylcholanthrene

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







13 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 30573465 Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice. 2019 Mar 6
2 23846873 Downregulation of mouse hepatic CYP3A protein by 3-methylcholanthrene does not require cytochrome P450-dependent metabolism. 2013 Oct 1
3 21832258 Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction. 2011 Sep 1
4 19451401 Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers. 2009 Aug 1
5 18559486 Blood monocyte-derived neohepatocytes as in vitro test system for drug metabolism. 2008 Sep 1
6 18954002 [A study of conformational states of substrates of cytochrome P450 3A4]. 2008 Sep-Oct 1
7 16337070 Territrems B and C metabolism in human liver microsomes: major role of CYP3A4 and CYP3A5. 2006 Feb 1 1
8 15331414 Near completely humanized liver in mice shows human-type metabolic responses to drugs. 2004 Sep 1
9 11231298 Expression and induction of a large set of drug-metabolizing enzymes by the highly differentiated human hepatoma cell line BC2. 2001 Mar 1
10 10873607 Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. 2000 Jun 24 1
11 9454825 Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isozymes in human hepatocytes in primary culture. 1998 Feb 2
12 9536002 Oncostatin M down-regulates basal and induced cytochromes P450 in human hepatocytes. 1998 Apr 1
13 7585637 Inhibition of CYP1A2 and CYP3A4 by oltipraz results in reduction of aflatoxin B1 metabolism in human hepatocytes in primary culture. 1995 Dec 1 1