artemisinin

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







12 Article(s)
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1 27713827 Evaluation of a novel PXR-knockout in HepaRG cells. 2016 Oct 1
2 24886881 Artemisinin protects against dextran sulfate-sodium-induced inflammatory bowel disease, which is associated with activation of the pregnane X receptor. 2014 Sep 5 6
3 22252826 PXR variants and artemisinin use in Vietnamese subjects: frequency distribution and impact on the interindividual variability of CYP3A induction by artemisinin. 2012 Apr 3
4 22577882 Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms. 2012 Oct 1
5 22679214 Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. 2012 Sep 1
6 17521300 Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects. 2007 Jun 1
7 15761118 Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor. 2005 Jun 2
8 12619052 Characterisation of the human liver in vitro metabolic pattern of artemisinin and auto-induction in the rat by use of nonlinear mixed effects modelling. 2003 Mar 1
9 11432537 Pharmacokinetic interactions of antimalarial agents. 2001 1
10 10583023 Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin. 1999 Oct 2
11 10626755 Stereospecific analysis of omeprazole supports artemisinin as a potent inducer of CYP2C19. 1999 1
12 9728896 Artemisinin induces omeprazole metabolism in human beings. 1998 Aug 1