Pub. Date : 2012 Apr
PMID : 22252826
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | PXR variants and artemisinin use in Vietnamese subjects: frequency distribution and impact on the interindividual variability of CYP3A induction by artemisinin. | artemisinin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
2 | Here, we report the resequencing and genotyping of PXR variants in 75 Vietnamese individuals previously characterized for CYP3A enzyme activity after artemisinin exposure. | artemisinin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
3 | A trend of significance was observed between the level of CYP3A4 induction by artemisinin and two PXR variants, the 8118C T (Y328Y) and 10719A G variants. | artemisinin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |