Carbamazepine

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







146 Article(s)
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1 34671997 Sub-therapeutic colchicine levels in a patient treated for acute pericarditis in the setting of carbamazepine use: A case report. 2022 Apr 1
2 32737897 Drug-drug and drug-food interactions in an infant with early-onset SCN2A epilepsy treated with carbamazepine, phenytoin and a ketogenic diet. 2021 Mar 1
3 33671323 Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug-Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach. 2021 Feb 17 4
4 33756436 Associations between CYP3A4, CYP3A5 and SCN1A polymorphisms and carbamazepine metabolism in epilepsy: A meta-analysis. 2021 Jul 4
5 34495458 Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making. 2021 Nov 1
6 32446424 High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers. 2020 Apr - Jun 1
7 32910451 [Carbamazepine and quetiapine: a neglected, but highly relevant interaction]. 2020 1
8 33283769 Presence of allele CYP3A4*16 does not have any bearing on carbamazepine-induced adverse drug reactions in North Indian people with epilepsy. 2020 Sep-Oct 2
9 30785734 Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213. 2019 Mar 12 2
10 32082165 Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics. 2019 1
11 29384591 A clinically relevant decrease in abiraterone exposure associated with carbamazepine use in a patient with castration-resistant metastatic prostate cancer. 2018 May 1
12 29569712 Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine. 2018 Dec 1
13 29649093 Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker. 2018 Aug 3
14 29869546 The Use of Carbamazepine to Expedite Metabolism of Risperidone Long-Acting Injection Through Induction of CYP3A4 in a Patient With Extrapyramidal Symptoms. 2018 Jun 1 1
15 30581412 Pharmacokinetic Interactions of Clinical Interest Between Direct Oral Anticoagulants and Antiepileptic Drugs. 2018 1
16 27690733 Influence of diosmin on the metabolism and disposition of carbamazepine in healthy subjects. 2017 Oct 6
17 27776366 Effect of Piperine on the Metabolism and Pharmacokinetics of Carbamazepine in Healthy Volunteers. 2017 Jan 2
18 27821711 Low Potential of Basimglurant to Be Involved in Drug-Drug Interactions: Influence of Non-Michaelis-Menten P450 Kinetics on Fraction Metabolized. 2017 Jan 1
19 28215696 Recurrent venous thrombosis under rivaroxaban and carbamazepine for symptomatic epilepsy. 2017 Mar - Apr 2
20 29369597 How long does the pharmacokinetic interaction between carbamazepine and quetiapine last after carbamazepine withdrawal? 2017 Dec 6
21 26574235 4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation? 2016 Feb 3
22 26651976 Influence of CYP3A5 polymorphism on the pharmacokinetics of psychiatric drugs. 2016 1
23 26711482 Evaluation of cytochrome P450 inductions by anti-epileptic drug oxcarbazepine, 10-hydroxyoxcarbazepine, and carbamazepine using human hepatocytes and HepaRG cells. 2016 Sep 1
24 26936324 Prediction of drug-drug interactions with carbamazepine-10,11-epoxide using a new in vitro assay for epoxide hydrolase inhibition. 2016 Dec 1
25 27274257 Clinical efficacy of perampanel for partial-onset and primary generalized tonic-clonic seizures. 2016 1
26 27276192 Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients. 2016 Mar 2
27 27402728 CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity. 2016 Sep 1
28 27417180 An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software. 2016 Oct 1
29 27450623 Interactions between non-vitamin K oral anticoagulants and antiepileptic drugs. 2016 Oct 1
30 27650703 Correction to Concurrent Cooperativity and Substrate Inhibition in the Epoxidation of Carbamazepine by Cytochrome P450 3A4 Active Site Mutants Inspired by Molecular Dynamics Simulations. 2016 Oct 4 1
31 30085479 EFFECT OF CARBAMAZEPINE ON THE ACTIVITY OF CYP3A4 ISOENZYME IN PATIENTS WITH ALCOHOL ADDICTION. 2016 6
32 24898833 Treatment of hypopituitarism in patients receiving antiepileptic drugs. 2015 Feb 2
33 25438721 Evaluation of the potential for pharmacokinetic drug-drug interaction between armodafinil and carbamazepine in healthy adults. 2015 Feb 1 1
34 25545162 Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations. 2015 Jan 27 12
35 25624269 Effect of resveratrol on the pharmacokinetics of carbamazepine in healthy human volunteers. 2015 May 2
36 25656284 Sertraline-induced potentiation of the CYP3A4-dependent neurotoxicity of carbamazepine: an in vitro study. 2015 Mar 3
37 26315684 Evaluation of Cytochrome P450 (CYP) 3A4-Based Interactions of Levomilnacipran with Ketoconazole, Carbamazepine or Alprazolam in Healthy Subjects. 2015 Oct 1
38 26421491 Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in monotherapy and bitherapy. 2015 Nov 1
39 26516577 Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies. 2015 Oct 1
40 24406279 Pharmacogenetic potential biomarkers for carbamazepine adverse drug reactions and clinical response. 2014 1
41 24691829 Effect of Sophora flavescens on the pharmacokinetics of carbamazepine in rats. 2014 Dec 3
42 24695353 Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity. 2014 Jul 5
43 24817818 Effects of EPHX1 and CYP3A4 polymorphisms on carbamazepine metabolism in epileptic patients. 2014 2
44 24861996 Association of ABCB1, CYP3A4, EPHX1, FAS, SCN1A, MICA, and BAG6 polymorphisms with the risk of carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis in Chinese Han patients with epilepsy. 2014 Aug 1
45 25495409 Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy. 2014 1
46 25561870 Modulation of CYP2D6 and CYP3A4 metabolic activities by Ferula asafetida resin. 2014 Dec 1
47 23212742 Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia. 2013 May 1
48 23252947 Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy. 2013 Jan 2
49 23480152 Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist. 2013 1
50 23716885 Effect of combination of aripiprazole with carbamazepine and fluvoxamine on liver functions in experimental animals. 2013 Mar-Apr 1