23 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34031539 | Advanced oxidation protein products downregulate CYP1A2 and CYP3A4 expression and activity via the NF-κB-mediated signaling pathway in vitro and in vivo. | 2021 Sep | 1 |
2 | 34430783 | In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology. | 2021 Aug | 1 |
3 | 31393259 | Granzyme B and miR-378a Interaction in Acetaminophen Toxicity in Children. | 2020 | 2 |
4 | 32455711 | Development of 3D Hepatic Constructs Within Polysaccharide-Based Scaffolds with Tunable Properties. | 2020 May 21 | 1 |
5 | 30587336 | Inhibition of cytochrome P450 3A protein degradation and subsequent increase in enzymatic activity through p38 MAPK activation by acetaminophen and salicylate derivatives. | 2019 Jan 29 | 6 |
6 | 31305025 | Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease. | 2019 Nov | 1 |
7 | 31892214 | Flow-Based Three-Dimensional Co-Culture Model for Long-Term Hepatotoxicity Prediction. | 2019 Dec 27 | 1 |
8 | 28341123 | Acetaminophen analog N-acetyl-m-aminophenol, but not its reactive metabolite, N-acetyl-p-benzoquinone imine induces CYP3A activity via inhibition of protein degradation. | 2017 May 6 | 3 |
9 | 28729056 | Discovery and structure-activity relationship of auriculatone: A potent hepatoprotective agent against acetaminophen-induced liver injury. | 2017 Aug 15 | 1 |
10 | 28951593 | MicroRNA regulation of CYP 1A2, CYP3A4 and CYP2E1 expression in acetaminophen toxicity. | 2017 Sep 26 | 2 |
11 | 26869439 | Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity. | 2016 Feb | 1 |
12 | 24498291 | Understanding a substrate's product regioselectivity in a family of enzymes: a case study of acetaminophen binding in cytochrome P450s. | 2014 | 1 |
13 | 22913318 | Targeting the pregnane X receptor in liver injury. | 2012 Nov | 1 |
14 | 21111054 | Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2. | 2011 May-Jun | 1 |
15 | 21194699 | In vitro cytochrome P450 activity: development and validation of a sensitive high performance liquid chromatography-tandem mass spectrometry method for the quantification of six probe metabolites after derivatization with pyridine-3-sulfonyl chloride in an aqueous environment. | 2011 Feb 11 | 1 |
16 | 19219744 | Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes. | 2009 Jan | 2 |
17 | 19460945 | Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity. | 2009 Aug | 6 |
18 | 15078344 | Characterization of the acetaminophen-induced degradation of cytochrome P450-3A4 and the proteolytic pathway. | 2004 Apr | 5 |
19 | 11811955 | The paradoxical effect of acetaminophen on CYP3A4 activity and content in transfected HepG2 cells. | 2002 Feb 1 | 5 |
20 | 10678302 | Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature. | 2000 Feb | 1 |
21 | 10741631 | Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation. | 2000 Mar | 1 |
22 | 9246016 | The effect of omeprazole pretreatment on acetaminophen metabolism in rapid and slow metabolizers of S-mephenytoin. | 1997 Jul | 2 |
23 | 8387297 | Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. | 1993 Apr 22 | 4 |