1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea

hypocretin receptor 1 ; Homo sapiens







16 Article(s)
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1 34635803 Orexin-1 receptor signaling in ventral tegmental area mediates cue-driven demand for cocaine. 2022 Feb 1
2 31526801 Persistent effects of the orexin-1 receptor antagonist SB-334867 on motivation for the fast acting opioid remifentanil. 2020 Mar 15 5
3 32061874 Orexin-1 receptor blockade differentially affects spatial and visual discrimination memory facilitation by intracranial self-stimulation. 2020 Mar 1
4 30700376 Orexin-A signaling in the paraventricular nucleus promote gastric acid secretion and gastric motility through the activation neuropeptide Y Y1 receptors and modulated by the hypothalamic lateral area. 2019 Apr 1
5 29953904 Increased training compensates for OX1R blockage-impairment of spatial memory and c-Fos expression in different cortical and subcortical areas. 2018 Nov 1 1
6 27523303 Orexin-1 receptor blockade suppresses compulsive-like alcohol drinking in mice. 2016 Nov 1
7 25515760 Orexin A upregulates the protein expression of OX1R and enhances the proliferation of SGC-7901 gastric cancer cells through the ERK signaling pathway. 2015 Feb 1
8 25586545 Effect of orexin A on apoptosis in BGC-823 gastric cancer cells via OX1R through the AKT signaling pathway. 2015 May 2
9 26049058 Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep. 2015 Sep 15 1
10 22830647 N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking. 2014 Mar 2
11 24592206 Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use. 2014 2
12 24685412 Orexin-A microinjection into the rostral ventromedial medulla causes antinociception on formalin test. 2014 Jul 1
13 23518606 A role for hypocretin/orexin receptor-1 in cue-induced reinstatement of nicotine-seeking behavior. 2013 Aug 1
14 20147556 Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior. 2010 Feb 10 3
15 19886391 Orexin A-induced extracellular calcium influx in prefrontal cortex neurons involves L-type calcium channels. 2009 Jun 1
16 18354023 Hypocretin-1 potentiates NMDA receptor-mediated somatodendritic secretion from locus ceruleus neurons. 2008 Mar 19 2