Lysine

lysine acetyltransferase 2B ; Homo sapiens







50 Article(s)
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1 34555274 P300/CBP-associated factor (PCAF)-mediated acetylation of Fascin at lysine 471 inhibits its actin-bundling activity and tumor metastasis in esophageal cancer. 2021 Dec 3
2 30833716 p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity. 2019 Mar 4 1
3 29440709 BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis. 2018 Apr 1
4 29555684 Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5. 2018 May 11 5
5 26802082 Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10. 2016 Jun 1
6 25800736 PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. 2015 Apr 20 1
7 25855960 Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma. 2015 Apr 9 1
8 24686445 PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system. 2014 Apr 1 1
9 24732800 CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells. 2014 Jun 2
10 23760262 Histone deacetylase 3 regulates cyclin A stability. 2013 Jul 19 1
11 23932781 Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth. 2013 Aug 22 1
12 24037888 PCAF impairs endometrial receptivity and embryo implantation by down-regulating β3-integrin expression via HOXA10 acetylation. 2013 Nov 2
13 22207202 Mapping acetylation sites in E2A identifies a conserved lysine residue in activation domain 1 that promotes CBP/p300 recruitment and transcriptional activation. 2012 May 1
14 22547391 PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1. 2012 Aug 1
15 24832227 HIV-1 Tat Binding to PCAF Bromodomain: Structural Determinants from Computational Methods. 2012 Aug 13 1
16 21416054 Regulation of the oncoprotein KLF8 by a switch between acetylation and sumoylation. 2011 Feb 1
17 20363750 Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2. 2010 May 28 1
18 20601085 Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation. 2010 Oct 1
19 19015268 Autoacetylation regulates P/CAF nuclear localization. 2009 Jan 16 1
20 19351588 Multiple lysine methylation of PCAF by Set9 methyltransferase. 2009 Mar 27 2
21 19483727 Degradation of cyclin A is regulated by acetylation. 2009 Jul 23 1
22 19773423 The transcriptional co-activator PCAF regulates cdk2 activity. 2009 Nov 1
23 18250157 Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription. 2008 Apr 1
24 18400184 Structural basis of site-specific histone recognition by the bromodomains of human coactivators PCAF and CBP/p300. 2008 Apr 4
25 17301242 Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5. 2007 Feb 20 1
26 17627840 A quantitative study on the in vitro and in vivo acetylation of high mobility group A1 proteins. 2007 Sep 24
27 17884818 Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation. 2007 Nov 30 3
28 16135803 p73 Interacts with human immunodeficiency virus type 1 Tat in astrocytic cells and prevents its acetylation on lysine 28. 2005 Sep 1
29 12419806 Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65. 2003 Jan 24 1
30 12758070 Functional interplay between CBP and PCAF in acetylation and regulation of transcription factor KLF13 activity. 2003 May 30 1
31 12888487 Mechanisms of P/CAF auto-acetylation. 2003 Aug 1 1
32 14661947 Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates. 2003 Dec 16 4
33 11931765 Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain. 2002 Mar 6
34 12374802 Acetylation of interferon regulatory factor-7 by p300/CREB-binding protein (CBP)-associated factor (PCAF) impairs its DNA binding. 2002 Dec 20 1
35 12486002 Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF. 2002 Dec 16 2
36 11486036 Regulation of transcription factor YY1 by acetylation and deacetylation. 2001 Sep 2
37 11509661 Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP. 2001 Sep 1
38 11514574 The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator. 2001 Oct 19 1
39 10777508 p300/CBP-associated factor histone acetyltransferase processing of a peptide substrate. Kinetic analysis of the catalytic mechanism. 2000 Jul 21 1
40 10852958 Regulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBP. 2000 Jun 20 1
41 10891493 Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. 2000 Aug 2
42 10944526 CREB-binding protein/p300 activates MyoD by acetylation. 2000 Nov 3 1
43 11046145 Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. 2000 Nov 2
44 11118214 P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. 2000 Dec 15 1
45 9880483 Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates. 1999 Jan 15 2
46 9891054 p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. 1999 Feb 2
47 10207070 Specific acetylation of chromosomal protein HMG-17 by PCAF alters its interaction with nucleosomes. 1999 May 2
48 10619020 Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program. 1999 Nov 1
49 9744860 DNA damage activates p53 through a phosphorylation-acetylation cascade. 1998 Sep 15 1
50 9809067 Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome. 1998 Oct 1