Title : Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation.

Pub. Date : 2007 Nov 30

PMID : 17884818






3 Functional Relationships(s)
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1 An in vivo acetylation assay using 293T cells revealed that Fli1 is mainly acetylated by the histone acetyltransferase activity of p300/CBP-associated factor (PCAF) at lysine 380. Lysine lysine acetyltransferase 2B Homo sapiens
2 An in vivo acetylation assay using 293T cells revealed that Fli1 is mainly acetylated by the histone acetyltransferase activity of p300/CBP-associated factor (PCAF) at lysine 380. Lysine lysine acetyltransferase 2B Homo sapiens
3 These results indicate that PCAF-dependent acetylation of lysine 380 abrogates repressor function of Fli1 with respect to collagen gene expression. Lysine lysine acetyltransferase 2B Homo sapiens