| 1 |
35331893 | Homing of granulocytes transfused in perineal cellulitis in a RAC2 deficiency child monitored by chimerism quantification methods. | 2022 Mar 21 |
1 |
| 2 |
32758662 | The protein kinase A negatively regulates reactive oxygen species production by phosphorylating gp91phox/NOX2 in human neutrophils. | 2020 Nov 20 |
1 |
| 3 |
30723080 | Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects. | 2019 May 2 |
5 |
| 4 |
31071452 | Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections. | 2019 Aug |
1 |
| 5 |
23875749 | Interaction of inducible nitric oxide synthase with rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: implication in microbial killing. | 2014 Jan 20 |
1 |
| 6 |
21576984 | Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2. | 2011 |
2 |
| 7 |
19414794 | Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency. | 2009 May 15 |
1 |
| 8 |
19625648 | Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2. | 2009 Aug 15 |
1 |
| 9 |
18347018 | Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism. | 2008 May 9 |
1 |
| 10 |
17548354 | Tripartite chimeras comprising functional domains derived from the cytosolic NADPH oxidase components p47phox, p67phox, and Rac1 elicit activator-independent superoxide production by phagocyte membranes: an essential role for anionic membrane phospholipids. | 2007 Jul 27 |
1 |
| 11 |
15847608 | HIV-1 Nef regulates the release of superoxide anions from human macrophages. | 2005 Sep 1 |
1 |
| 12 |
16081809 | Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome. | 2005 Aug 15 |
1 |
| 13 |
16115878 | Interleukin-8-induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts. | 2005 Nov 4 |
1 |
| 14 |
16204621 | Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation. | 2005 Nov |
1 |
| 15 |
15170212 | Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. | 2004 Jul |
2 |
| 16 |
12352324 | Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes. | 2002 Oct |
1 |
| 17 |
12411394 | Rac-dependent monocyte chemoattractant protein-1 production is induced by nutrient deprivation. | 2002 Nov 1 |
1 |
| 18 |
12468931 | RAC2 GTPase deficiency and myeloid cell dysfunction in human and mouse. | 2002 Dec |
1 |
| 19 |
12471136 | Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation. | 2002 Dec 15 |
1 |
| 20 |
11445809 | Clinical features of a human Rac2 mutation: a complex neutrophil dysfunction disease. | 2001 Jul |
1 |
| 21 |
10758162 | Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation. | 2000 Apr 25 |
1 |
| 22 |
10393079 | The mechanism of activation of NADPH oxidase in the cell-free system: the activation process is primarily catalytic and not through the formation of a stoichiometric complex. | 1999 Jul 15 |
1 |
| 23 |
10540223 | Expression and translocation of Rac2 in eosinophils during superoxide generation. | 1999 Oct |
1 |
| 24 |
9624165 | Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox). | 1998 Jun 19 |
1 |
| 25 |
9255350 | [Signal transduction by Rac small G proteins in phagocytes]. | 1997 |
1 |
| 26 |
8663333 | Assembly of the human neutrophil NADPH oxidase involves binding of p67phox and flavocytochrome b to a common functional domain in p47phox. | 1996 Jul 19 |
1 |
| 27 |
8961931 | Membrane association of Rac is required for high activity of the respiratory burst oxidase. | 1996 Dec 10 |
1 |
| 28 |
7616102 | Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors. | 1995 Jul |
1 |
| 29 |
7654216 | The assembly of neutrophil NADPH oxidase: effects of mastoparan and its synthetic analogues. | 1995 Sep 1 |
1 |
| 30 |
8117710 | p21rac does not participate in the early interaction between p47-phox and cytochrome b558 that leads to phagocyte NADPH oxidase activation in vitro. | 1994 Mar 8 |
1 |
| 31 |
8141770 | Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane. | 1994 Mar 15 |
1 |
| 32 |
8305740 | Regulation of NADPH oxidase activity by Rac GTPase activating protein(s). | 1993 Nov |
2 |
| 33 |
8387355 | Requirement for posttranslational processing of Rac GTP-binding proteins for activation of human neutrophil NADPH oxidase. | 1993 Mar |
1 |
| 34 |
1316893 | Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins. | 1992 May 25 |
2 |
| 35 |
1328203 | Inhibition of superoxide production in B lymphocytes by rac antisense oligonucleotides. | 1992 Oct 15 |
2 |
| 36 |
1464587 | Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase. | 1992 Dec 25 |
1 |