| 1 |
34992144 | Small-Molecule NSC59984 Induces Mutant p53 Degradation through a ROS-ERK2-MDM2 Axis in Cancer Cells. | 2022 Apr 1 |
1 |
| 2 |
34997083 | PEA-15 engages in allosteric interactions using a common scaffold in a phosphorylation-dependent manner. | 2022 Jan 7 |
2 |
| 3 |
35110502 | RSK-Mediated Non-canonical Activation of EphA2 by Tamoxifen. | 2022 |
1 |
| 4 |
35174144 | Cell-Free Fat Extract Prevents Tail Suspension-Induced Bone Loss by Inhibiting Osteocyte Apoptosis. | 2022 |
1 |
| 5 |
35196191 | Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions. | 2022 Feb 23 |
1 |
| 6 |
35546143 | TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC. | 2022 May 11 |
1 |
| 7 |
33152171 | Multi-kinase framework promotes proliferation and invasion of lung adenocarcinoma through activation of dynamin-related protein 1. | 2021 Feb |
1 |
| 8 |
33971490 | Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors. | 2021 Jun 15 |
1 |
| 9 |
34202904 | RSK Isoforms in Acute Myeloid Leukemia. | 2021 Jun 24 |
1 |
| 10 |
34314419 | Ras/ERK and PI3K/AKT signaling differentially regulate oncogenic ERG mediated transcription in prostate cells. | 2021 Jul |
1 |
| 11 |
34403210 | Activation of ERK-Drp1 signaling promotes hypoxia-induced Aβ accumulation by upregulating mitochondrial fission and BACE1 activity. | 2021 Oct |
1 |
| 12 |
34564169 | RSK1 vs. RSK2 Inhibitory Activity of the Marine β-Carboline Alkaloid Manzamine A: A Biochemical, Cervical Cancer Protein Expression, and Computational Study. | 2021 Sep 7 |
1 |
| 13 |
34699606 | Zinc induces reactive astrogliosis through ERK-dependent activation of Stat3 and promotes synaptic degeneration. | 2021 Dec |
2 |
| 14 |
34779126 | Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation. | 2021 Dec 7 |
1 |
| 15 |
34837907 | A Clinical Evaluation of Circulating MiR-106a and Raf-1 as Breast Cancer Diagnostic and Prognostic Markers. | 2021 Nov 1 |
2 |
| 16 |
34844526 | Integrated computational approach for in silico design of new purinyl pyridine derivatives as B-Raf kinase inhibitors. | 2021 Nov 29 |
1 |
| 17 |
34859235 | Targeted therapy strategies for melanoma brain metastasis. | 2021 Nov |
1 |
| 18 |
31215069 | NAD(P)H Quinone Dehydrogenase 1 Ablation Inhibits Activation of the Phosphoinositide 3-Kinase/Akt Serine/Threonine Kinase and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Pathways and Blocks Metabolic Adaptation in Hepatocellular Carcinoma. | 2020 Feb |
1 |
| 19 |
33073187 | Role of the Helix-8 and C-Terminal Tail in Regulating Proteinase Activated Receptor 2 Signaling. | 2020 Oct 9 |
1 |
| 20 |
33133138 | Combining PARP and DNA-PK Inhibitors With Irradiation Inhibits HPV-Negative Head and Neck Cancer Squamous Carcinoma Growth. | 2020 |
1 |
| 21 |
30535970 | HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia. | 2019 Feb |
1 |
| 22 |
30835471 | Role of Conserved Histidine and Serine in the HCXXXXXRS Motif of Human Dual-Specificity Phosphatase 5. | 2019 Apr 22 |
1 |
| 23 |
30962349 | ERK1/2 phosphorylates HIF-2α and regulates its activity by controlling its CRM1-dependent nuclear shuttling. | 2019 Apr 8 |
1 |
| 24 |
30972179 | Regulation of Krüppel-like factor 8 by the NEDD4 E3 ubiquitin ligase. | 2019 |
1 |
| 25 |
31013829 | Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling. | 2019 Apr 12 |
1 |
| 26 |
31053301 | Negative feedback regulation of ErbB4 tyrosine kinase activity by ERK-mediated non-canonical phosphorylation. | 2019 Jun 25 |
1 |
| 27 |
31184227 | Ras-ERK signalling represses H1.4 phosphorylation at serine 36 to promote non-small-cell lung carcinoma cells growth and migration. | 2019 Dec |
1 |
| 28 |
31385665 | Nuclear ERK Translocation is Mediated by Protein Kinase CK2 and Accelerated by Autophosphorylation. | 2019 |
2 |
| 29 |
31387295 | CDDO-Me Selectively Attenuates CA1 Neuronal Death Induced by Status Epilepticus via Facilitating Mitochondrial Fission Independent of LONP1. | 2019 Aug 5 |
1 |
| 30 |
28383811 | HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy. | 2018 Feb |
2 |
| 31 |
29197575 | Trametinib suppresses HIV-1 replication by interfering with the disassembly of human immunodeficiency virus type 1 capsid core. | 2018 Jan 8 |
1 |
| 32 |
29380370 | Endothelial immune activation programmes cell-fate decisions and angiogenesis by inducing angiogenesis regulator DLL4 through TLR4-ERK-FOXC2 signalling. | 2018 Apr 15 |
1 |
| 33 |
29445193 | Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. | 2018 Feb 14 |
1 |
| 34 |
29540527 | A biosensor for MAPK-dependent Lin28 signaling. | 2018 May 15 |
3 |
| 35 |
29545175 | RUVBL1, a novel C-RAF-binding protein, activates the RAF/MEK/ERK pathway to promote lung cancer tumorigenesis. | 2018 Apr 15 |
2 |
| 36 |
30009260 | Phosphorylation of human TRM9L integrates multiple stress-signaling pathways for tumor growth suppression. | 2018 Jul |
1 |
| 37 |
30380514 | The fungal metabolite cyclonerodiol inhibits IL-4/IL-13 induced Stat6-signaling through blocking the association of Stat6 with p38, ERK1/2 and p300. | 2018 Dec |
1 |
| 38 |
30381640 | [Elucidation of a New Mechanism of Onset of Insulin Resistance: Effects of Statins and Tumor Necrosis Factor-α on Insulin Signal Transduction]. | 2018 |
2 |
| 39 |
27689466 | Activation of estrogen receptor α by estradiol and cisplatin induces platinum-resistance in ovarian cancer cells. | 2017 Sep 2 |
1 |
| 40 |
27924567 | The Nuclear Translocation of ERK. | 2017 |
1 |
| 41 |
28393288 | Differential effects of p38 MAP kinase inhibitors SB203580 and SB202190 on growth and migration of human MDA-MB-231 cancer cell line. | 2017 Aug |
1 |
| 42 |
28887309 | Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation. | 2017 Oct 20 |
6 |
| 43 |
25915848 | Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability. | 2016 Feb 4 |
2 |
| 44 |
26303380 | Effects of cerulein on keratin 8 phosphorylation and perinuclear reorganization in pancreatic cancer cells: Involvement of downregulation of protein phosphatase 2A and alpha4. | 2016 Dec |
2 |
| 45 |
26346493 | Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome. | 2016 Feb |
1 |
| 46 |
26846853 | β-Arrestins Negatively Regulate the Toll Pathway in Shrimp by Preventing Dorsal Translocation and Inhibiting Dorsal Transcriptional Activity. | 2016 Apr 1 |
3 |
| 47 |
27009860 | ERK2 phosphorylation of EBNA1 serine 383 residue is important for EBNA1-dependent transactivation. | 2016 May 3 |
4 |
| 48 |
27055868 | MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation. | 2016 Jul |
1 |
| 49 |
27080258 | Extracellular Signal-regulated Kinase (ERK)-dependent Phosphorylation of Y-Box-binding Protein 1 (YB-1) Enhances Gene Expression in Granulosa Cells in Response to Follicle-stimulating Hormone (FSH). | 2016 Jun 3 |
2 |
| 50 |
27293988 | ERK2 phosphorylates Krüppel-like factor 8 protein at serine 48 to maintain its stability. | 2016 |
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