sulforaphane

mitogen-activated protein kinase 1 ; Homo sapiens







24 Article(s)
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1 32323779 Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation. 2020 Apr 1
2 32387680 Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract. 2020 Sep 1
3 32443471 Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer. 2020 May 18 7
4 29440765 Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling. 2018 Feb 13 1
5 29707130 Sulforaphane suppresses oral cancer cell migration by regulating cathepsin S expression. 2018 Apr 3 3
6 28944886 Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway. 2017 Nov 11
7 25070589 Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells. 2015 Jan 1
8 25933243 Neuroprotective effect of sulforaphane against methylglyoxal cytotoxicity. 2015 Jun 15 1
9 26296464 Sulforaphane induces apoptosis in adipocytes via Akt/p70s6k1/Bad inhibition and ERK activation. 2015 Oct 2 2
10 24671668 Sulforaphane inhibits IL-1β-induced proliferation of rheumatoid arthritis synovial fibroblasts and the production of MMPs, COX-2, and PGE2. 2014 Oct 1
11 24747121 Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase and ERK. 2014 Aug 28 2
12 24952354 Sulforaphane induces autophagy through ERK activation in neuronal cells. 2014 Aug 25 5
13 23417518 Growth inhibition and apoptosis of neuroblastoma cells through ROS-independent MEK/ERK activation by sulforaphane. 2013 Jul 2
14 22565590 Effect of sulforaphane on growth inhibition in human brain malignant glioma GBM 8401 cells by means of mitochondrial- and MEK/ERK-mediated apoptosis pathway. 2012 Jul 1
15 25683399 Synergy between sulforaphane and selenium in the up-regulation of thioredoxin reductase and protection against hydrogen peroxide-induced cell death in human hepatocytes. 2012 Jul 15 1
16 20405237 Protective effect of sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage. 2010 Jun 3
17 19653226 Protective effect of sulforaphane on indomethacin-induced cytotoxicity via heme oxygenase-1 expression in human intestinal Int 407 cells. 2009 Sep 5
18 19885601 Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors. 2009 Dec 2
19 18980980 Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis. 2008 Nov 1 1
20 17183064 Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells. 2007 May 1
21 16272172 ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. 2006 Mar 3
22 15896333 Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. 2005 Jun 1 3
23 16033772 Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells. 2005 Dec 8
24 11768769 Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). 2001 Aug-Nov 1