| 1 |
34715309 | Effects of miRNAs in exosomes derived from α-synuclein overexpressing SH-SY5Y cells on autophagy and inflammation of microglia. | 2022 Jan |
2 |
| 2 |
34797524 | ERK inhibition in glioblastoma is associated with autophagy activation and tumorigenesis suppression. | 2022 Jan |
1 |
| 3 |
35571122 | Effect of Combined Mycophenolate and Rapamycin Treatment on Kidney Fibrosis in Murine Lupus Nephritis. | 2022 |
1 |
| 4 |
33748286 | ROS-ERK Pathway as Dual Mediators of Cellular Injury and Autophagy-Associated Adaptive Response in Urinary Protein-Irritated Renal Tubular Epithelial Cells. | 2021 |
1 |
| 5 |
34421360 | Rapamycin and trametinib: a rational combination for treatment of NSCLC. | 2021 |
3 |
| 6 |
32104716 | Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides. | 2020 |
1 |
| 7 |
32736702 | Activation of ERK1/2-mTORC1-NOX4 mediates TGF-β1-induced epithelial-mesenchymal transition and fibrosis in retinal pigment epithelial cells. | 2020 Aug 27 |
2 |
| 8 |
30672370 | Bisperoxovanadium Mediates Neuronal Protection through Inhibition of PTEN and Activation of PI3K/AKT-mTOR Signaling after Traumatic Spinal Injuries. | 2019 Sep 15 |
1 |
| 9 |
31315300 | HEMA Effects on Autophagy Mechanism in Human Dental Pulp Stem Cells. | 2019 Jul 16 |
1 |
| 10 |
31358596 | Effect of mycophenolate and rapamycin on renal fibrosis in lupus nephritis. | 2019 Aug 15 |
2 |
| 11 |
29475988 | HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. | 2018 Apr 1 |
1 |
| 12 |
27399332 | Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth. | 2017 Feb 9 |
1 |
| 13 |
28734155 | Activation of mTOR is involved in anti-β2GPI/β2GPI-induced expression of tissue factor and IL-8 in monocytes. | 2017 Sep |
1 |
| 14 |
28963126 | EGF regulation of proximal tubule cell proliferation and VEGF-A secretion. | 2017 Sep |
1 |
| 15 |
27616194 | Rapamycin regulates the proliferation of Huh7, a hepatocellular carcinoma cell line, by up-regulating p53 expression. | 2016 Oct 7 |
1 |
| 16 |
25758096 | The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation. | 2015 Jul |
2 |
| 17 |
26337526 | Down-regulation of mitogen-activated protein kinases and nuclear factor-κB signaling is involved in rapamycin suppression of TLR2-induced inflammatory response in monocytic THP-1 cells. | 2015 Oct |
1 |
| 18 |
23741975 | Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosis in vitro and in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase signaling pathways. | 2014 Mar |
3 |
| 19 |
24676456 | The combination of rapamycin and MAPK inhibitors enhances the growth inhibitory effect on Nara-H cells. | 2014 Jun |
2 |
| 20 |
25116684 | Rapamycin-Induced apoptosis in HGF-stimulated lens epithelial cells by AKT/mTOR, ERK and JAK2/STAT3 pathways. | 2014 Aug 11 |
4 |
| 21 |
23403511 | Rapamycin increases pCREB, Bcl-2, and VEGF-A through ERK under normoxia. | 2013 Apr |
2 |
| 22 |
23426956 | Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin. | 2013 May |
1 |
| 23 |
23580233 | Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin. | 2013 Jul |
1 |
| 24 |
23607966 | mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. | 2013 Jul |
1 |
| 25 |
22057915 | Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells. | 2012 Jan |
2 |
| 26 |
22552366 | Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells. | 2012 Jul |
1 |
| 27 |
22617154 | Role of Toll-like receptor 2 in the immune response against hepadnaviral infection. | 2012 Sep |
2 |
| 28 |
21168265 | Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. | 2011 Feb 28 |
2 |
| 29 |
19856312 | Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells. | 2010 Jun 1 |
1 |
| 30 |
20512842 | Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways. | 2010 Jun |
11 |
| 31 |
19139116 | Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin. | 2009 Jan |
3 |
| 32 |
19539245 | Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model. | 2009 Jun |
1 |
| 33 |
18312854 | MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway. | 2008 May 2 |
1 |
| 34 |
18715846 | Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma. | 2008 Summer |
1 |
| 35 |
18958173 | Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM. | 2008 |
1 |
| 36 |
18981735 | Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy. | 2008 Dec |
3 |
| 37 |
16959214 | Malignant hematopoietic cells induce an increased expression of VEGFR-1 and VEGFR-3 on bone marrow endothelial cells via AKT and mTOR signalling pathways. | 2006 Oct 27 |
1 |
| 38 |
17041093 | Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts. | 2006 Oct |
2 |
| 39 |
15634685 | Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. | 2005 Mar 25 |
2 |
| 40 |
15696050 | Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin. | 2005 Jan |
1 |
| 41 |
15767555 | Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways. | 2005 Mar |
1 |
| 42 |
12543789 | Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways. | 2003 Jan 15 |
2 |
| 43 |
10048588 | MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor. | 1999 Feb |
1 |