suvorexant

hypocretin neuropeptide precursor ; Homo sapiens







27 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35022783 A double-blind, randomized, placebo-controlled trial of suvorexant for the treatment of vasomotor symptom-associated insomnia disorder in midlife women. 2022 Mar 14 1
2 34497544 Magnetic Resonance Spectroscopy in the Ventral Tegmental Area Distinguishes Responders to Suvorexant Prior to Treatment: A 4-Week Prospective Cohort Study. 2021 1
3 34933185 Blocking the orexin system following therapeutic exposure promoted between session habituation, but not PTSD symptom reduction. 2021 Dec 14 1
4 32224066 Suvorexant ameliorates cognitive impairments and pathology in APP/PS1 transgenic mice. 2020 Jul 1
5 32669442 Structure-based development of a subtype-selective orexin 1 receptor antagonist. 2020 Jul 28 1
6 30619717 Improvement of glycemic control by treatment for insomnia with suvorexant in type 2 diabetes mellitus. 2019 Mar 1
7 29289556 Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders. 2018 Jun 2
8 27860547 The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia. 2017 Jan 6 1
9 27909991 The Role of Orexins/Hypocretins in Alcohol Use and Abuse. 2017 1
10 28584695 Neuroendocrine, Autonomic, and Metabolic Responses to an Orexin Antagonist, Suvorexant, in Psychiatric Patients with Insomnia. 2017 Mar-Apr 1
11 28945327 Suvorexant as an orexin antagonist may regulate serum glucose levels in psychiatric patients with insomnia. 2017 Dec 1
12 28994603 Suvorexant: scientifically interesting, utility uncertain. 2017 Dec 1
13 26317591 Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of Insomnia. 2016 Jan 28 1
14 26864332 In vitro and in vivo characterisation of the metabolism and disposition of suvorexant in humans. 2016 Oct 2
15 27253658 Assessment of the Abuse Potential of the Orexin Receptor Antagonist, Suvorexant, Compared With Zolpidem in a Randomized Crossover Study. 2016 Aug 2
16 27390287 Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold-Hopping Approach. 2016 Oct 6 1
17 25397996 Suvorexant: something new for sleep? 2015 Feb 1
18 25969666 Suvorexant: The first orexin receptor antagonist to treat insomnia. 2015 Apr-Jun 2
19 24592206 Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use. 2014 1
20 24680372 Safety and efficacy of suvorexant during 1-year treatment of insomnia with subsequent abrupt treatment discontinuation: a phase 3 randomised, double-blind, placebo-controlled trial. 2014 May 2
21 25197807 Electroencephalographic power spectral density profile of the orexin receptor antagonist suvorexant in patients with primary insomnia and healthy subjects. 2014 Oct 1 1
22 25227290 Suvorexant: first global approval. 2014 Oct 2
23 23359095 Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status. 2013 Feb 1
24 22725839 Enantioselective synthesis of a dual orexin receptor antagonist. 2012 Jul 6 1
25 22920041 Update on emerging drugs for insomnia. 2012 Sep 2
26 23024835 ACS chemical neuroscience molecule spotlight on Suvorexant. 2012 Sep 19 1
27 21528938 Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305). 2011 Jun 1 4