Lysine

ubiquitin conjugating enzyme E2 I ; Homo sapiens







30 Article(s)
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1 33661764 SUMOylation promotes extracellular vesicle-mediated transmission of lncRNA ELNAT1 and lymph node metastasis in bladder cancer. 2021 Apr 15 1
2 32249212 SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. 2020 May 8 1
3 30631151 Sumoylation of Flotillin-1 promotes EMT in metastatic prostate cancer by suppressing Snail degradation. 2019 Apr 2
4 29773808 Quantitative SUMO proteomics reveals the modulation of several PML nuclear body associated proteins and an anti-senescence function of UBC9. 2018 May 17 2
5 28201649 A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR. 2017 Jun 1 1
6 28784659 Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. 2017 Sep 15 2
7 27501389 Is Transthyretin a Regulator of Ubc9 SUMOylation? 2016 2
8 26116533 Distinct functional modes of SUMOylation for retinoid X receptor alpha. 2015 Aug 14 1
9 24096733 TAB2, an important upstream adaptor of interleukin-1 signaling pathway, is subject to SUMOylation. 2014 Jan 1
10 23772552 Development of a high-throughput screen to detect inhibitors of TRPS1 sumoylation. 2013 Jun 2
11 22214662 The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G₁ arrest. 2012 Jan 15 1
12 22403398 Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity. 2012 May 4 2
13 23095757 Sumoylation of SAE2 C terminus regulates SAE nuclear localization. 2012 Dec 14 2
14 21288202 SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b. 2011 Apr 15 1
15 19107417 Purification of SUMO conjugating enzymes and kinetic analysis of substrate conjugation. 2009 1
16 19635459 Enhanced SUMOylation of proteins containing a SUMO-interacting motif by SUMO-Ubc9 fusion. 2009 Oct 9 2
17 19744555 Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene. 2009 Dec 1
18 17704809 Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response. 2008 Feb 7 1
19 17336575 Regulation of nuclear receptor and coactivator functions by the carboxyl terminus of ubiquitin-conjugating enzyme 9. 2007 2
20 18082607 PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. 2007 Dec 14 1
21 16732283 Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. 2006 Jun 2
22 15580297 Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net. 2005 Jan 27 1
23 16029420 Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner. 2005 Aug 1
24 16275321 Purification and activity assays for Ubc9, the ubiquitin-conjugating enzyme for the small ubiquitin-like modifier SUMO. 2005 1
25 15272016 In vitro modification of human centromere protein CENP-C fragments by small ubiquitin-like modifier (SUMO) protein: definitive identification of the modification sites by tandem mass spectrometry analysis of the isopeptides. 2004 Sep 17 1
26 12641448 Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex. 2003 Mar 25 3
27 11779867 Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity. 2002 Mar 15 1
28 11853669 Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. 2002 Feb 8 1
29 12226657 RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. 2002 Sep 12 1
30 10694430 Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9. 2000 Mar 15 1