Lysine

lysine acetyltransferase 5 ; Homo sapiens







49 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33907746 FACT subunit SUPT16H associates with BRD4 and contributes to silencing of antiviral interferon signaling. 2021 Apr 21 1
2 33938178 Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity. 2021 Mar 26 3
3 34331108 Repurposing proscillaridin A in combination with decitabine against embryonal rhabdomyosarcoma RD cells. 2021 Nov 1
4 34447288 Angiopoietin-like protein 4 is a chromatin-bound protein that enhances mammosphere formation in vitro and experimental triple-negative breast cancer brain and liver metastases in vivo. 2021 2
5 34621741 A Novel Mechanism of Ataxia Telangiectasia Mutated Mediated Regulation of Chromatin Remodeling in Hypoxic Conditions. 2021 3
6 32120841 Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression. 2020 Feb 27 2
7 32647127 EEF1A1 deacetylation enables transcriptional activation of remyelination. 2020 Jul 9 1
8 32822602 De Novo KAT5 Variants Cause a Syndrome with Recognizable Facial Dysmorphisms, Cerebellar Atrophy, Sleep Disturbance, and Epilepsy. 2020 Sep 3 2
9 32843577 Fe65 is the sole member of its family that mediates transcription regulated by the amyloid precursor protein. 2020 Sep 8 1
10 32960142 Digging Deeper into Breast Cancer Epigenetics: Insights from Chemical Inhibition of Histone Acetyltransferase TIP60 In Vitro. 2020 Oct 1
11 33155839 Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells. 2020 Nov 1
12 30154425 TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial-mesenchymal transition and metastasis in liver cancer. 2019 Jan 1
13 30400007 KAT5 promotes invasion and metastasis through C-MYC stabilization in ATC. 2019 Jan 1 1
14 30409912 Dynamic acetylation of the kinetochore-associated protein HEC1 ensures accurate microtubule-kinetochore attachment. 2019 Jan 11 4
15 30655546 Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy. 2019 Jan 17 1
16 31218831 Tip60-dependent acetylation of KDM2B promotes osteosarcoma carcinogenesis. 2019 Sep 2
17 29174981 Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer. 2018 Jan 15 2
18 28623334 Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion. 2017 Jun 16 1
19 26822153 Small RNAs Recruit Chromatin-Modifying Enzymes MMSET and Tip60 to Reconfigure Damaged DNA upon Double-Strand Break and Facilitate Repair. 2016 Apr 1 4
20 25560918 The chromodomain-containing histone acetyltransferase TIP60 acts as a code reader, recognizing the epigenetic codes for initiating transcription. 2015 1
21 26291311 KAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiation. 2015 Aug 20 2
22 23318425 DMAP1 is an essential regulator of ATM activity and function. 2014 Jan 23 1
23 24452550 Regulation and function of histone acetyltransferase MOF. 2014 Mar 1
24 24621507 Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. 2014 1
25 24835996 Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60. 2014 Jun 12 2
26 24927542 DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin. 2014 Jun 24 2
27 25301942 Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3. 2014 Dec 5 1
28 23238566 Stabilization of p21 (Cip1/WAF1) following Tip60-dependent acetylation is required for p21-mediated DNA damage response. 2013 Apr 1
29 23576563 ING5 is a Tip60 cofactor that acetylates p53 in response to DNA damage. 2013 Jun 15 2
30 24044023 Phosphorylation of Tip60 Tyrosine 327 by Abl Kinase Inhibits HAT Activity through Association with FE65. 2013 2
31 24096875 p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. 2013 Nov 1
32 22159227 Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin. 2012 Feb 1
33 22249179 New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor. 2012 Mar 2 2
34 22470428 Function of the active site lysine autoacetylation in Tip60 catalysis. 2012 4
35 22586264 SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60. 2012 Jul 4
36 22749149 Mechanistic links between ATM and histone methylation codes during DNA repair. 2012 2
37 23056207 Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. 2012 1
38 21157427 Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin. 2011 Feb 2 1
39 21463657 TRIM29 negatively regulates p53 via inhibition of Tip60. 2011 Jun 1
40 20160506 Tip60: connecting chromatin to DNA damage signaling. 2010 Mar 1 2
41 19783983 Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60. 2009 Nov 2
42 19800870 UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity. 2009 Dec 18 2
43 17551969 Tip60 modulates PLAGL2-mediated transactivation by acetylation. 2008 Feb 15 2
44 17704809 Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response. 2008 Feb 7 2
45 17923702 DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity. 2007 Dec 2
46 17189186 Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. 2006 Dec 28 1
47 12110674 A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3. 2002 Sep 20 1
48 12353039 Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair. 2002 Sep 26 2
49 10096020 Tip60 acetylates six lysines of a specific class in core histones in vitro. 1998 Dec 5