Title : DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity.

Pub. Date : 2007 Dec

PMID : 17923702






2 Functional Relationships(s)
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1 Furthermore, lysine 3016 of ATM is a substrate in vitro for the Tip60 histone acetyltransferase. Lysine lysine acetyltransferase 5 Homo sapiens
2 The acetylation of ATM on lysine 3016 by Tip60 is therefore a key step linking the detection of DNA damage and the activation of ATM kinase activity. Lysine lysine acetyltransferase 5 Homo sapiens