| 1 |
33677798 | Heterogenous chemosensitivity of a panel of organoid lines derived from small cell neuroendocrine carcinoma of the uterine cervix. | 2021 May |
2 |
| 2 |
28112927 | Selective Inhibitors of Human Liver Carboxylesterase Based on a β-Lapachone Scaffold: Novel Reagents for Reaction Profiling. | 2017 Feb 23 |
1 |
| 3 |
28345025 | Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma. | 2017 Mar 17 |
1 |
| 4 |
26900660 | Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2. | 2016 Apr 13 |
2 |
| 5 |
24988246 | The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect. | 2014 |
1 |
| 6 |
20833148 | Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11. | 2011 Jan 1 |
4 |
| 7 |
20649590 | Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin. | 2010 Aug |
1 |
| 8 |
20653675 | Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients. | 2010 Aug |
10 |
| 9 |
19225040 | Different inhibitory effects in rat and human carboxylesterases. | 2009 May |
2 |
| 10 |
18023188 | Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). | 2008 Feb 15 |
1 |
| 11 |
18188187 | An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11. | 2008 Mar |
1 |
| 12 |
17264798 | Human carboxylesterase 1A2 expressed from carboxylesterase 1A1 and 1A2 genes is a potent predictor of CPT-11 cytotoxicity in vitro. | 2007 Jan |
4 |
| 13 |
15897249 | Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors. | 2005 May |
2 |
| 14 |
14967028 | Molecular modeling of CPT-11 metabolism by carboxylesterases (CEs): use of pnb CE as a model. | 2004 Feb 24 |
4 |
| 15 |
14617791 | Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies. | 2003 Nov |
5 |
| 16 |
12171903 | Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. | 2002 Aug |
5 |
| 17 |
11716702 | Identification and activities of human carboxylesterases for the activation of CPT-11, a clinically approved anticancer drug. | 2001 Nov-Dec |
1 |