remdesivir

carboxylesterase 1 ; Homo sapiens







5 Article(s)
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1 34774545 Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans. 2022 Jan 5 1
2 34125594 Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells. 2021 Aug 17 2
3 34370586 Single-Cell RNA Sequencing Supports Preferential Bioactivation of Remdesivir in the Liver. 2021 Sep 17 2
4 34510834 The COVID-19 Medicine Remdesivir Is Therapeutically Activated by Carboxylesterase-1, and Excessive Hydrolysis Increases Cytotoxicity. 2021 Sep 1
5 34918945 Cannabidiol Inhibits In Vitro Human Liver Microsomal Metabolism of Remdesivir: A Promising Adjuvant for COVID-19 Treatment. 2021 Dec 16 4