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33103454 | GPR40 deficiency is associated with hepatic FAT/CD36 upregulation, steatosis, inflammation, and cell injury in C57BL/6 mice. | 2021 Jan 1 |
1 |
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34349026 | CPL207280, a Novel G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1-Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals. | 2021 Oct |
2 |
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34489696 | FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity in Mice. | 2021 |
3 |
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34774873 | GPR40 agonist inhibits NLRP3 inflammasome activation via modulation of nuclear factor-κB and sarco/endoplasmic reticulum Ca2+-ATPase. | 2021 Dec 15 |
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| 5 |
31740001 | Stimulation of insulin secretion by acetylenic fatty acids in insulinoma MIN6 cells through FFAR1. | 2020 Jan 29 |
2 |
| 6 |
31812788 | A high-fat diet enriched in medium chain triglycerides triggers hepatic thermogenesis and improves metabolic health in lean and obese mice. | 2020 Mar |
2 |
| 7 |
32728158 | Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease. | 2020 Jul 29 |
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| 8 |
31002464 | Free fatty acid receptors, G protein-coupled receptor 120 and G protein-coupled receptor 40, are essential for oil-induced gastric inhibitory polypeptide secretion. | 2019 Nov |
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| 9 |
31664108 | GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells. | 2019 Oct 29 |
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| 10 |
29748290 | Endogenous Fatty Acids Are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion. | 2018 Oct |
4 |
| 11 |
29931581 | The involvement of free fatty acid-GPR40/FFAR1 signaling in chronic social defeat stress-induced pain prolongation in C57BL/6J male mice. | 2018 Aug |
2 |
| 12 |
27611773 | GPR40 mediates potential positive effects of a saturated fatty acid enriched diet on bone. | 2017 Feb |
4 |
| 13 |
28723961 | Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice. | 2017 |
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| 14 |
29031729 | Point mutation of Ffar1 abrogates fatty acid-dependent insulin secretion, but protects against HFD-induced glucose intolerance. | 2017 Oct |
4 |
| 15 |
29568424 | Optical control of GPR40 signalling in pancreatic β-cells. | 2017 Nov 1 |
1 |
| 16 |
26974308 | Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. | 2016 Apr |
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| 17 |
27700527 | The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1. | 2016 Nov |
2 |
| 18 |
26408932 | Free fatty acid receptor 1 (FFAR1/GPR40) signaling affects insulin secretion by enhancing mitochondrial respiration during palmitate exposure. | 2015 Dec |
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| 19 |
23331570 | Lack of GPR40/FFAR1 does not induce diabetes even under insulin resistance condition. | 2013 Jun |
2 |
| 20 |
23335512 | The free fatty acid receptor G protein-coupled receptor 40 (GPR40) protects from bone loss through inhibition of osteoclast differentiation. | 2013 Mar 1 |
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| 21 |
23831422 | Activation of tongue-expressed GPR40 and GPR120 by non caloric agonists is not sufficient to drive preference in mice. | 2013 Oct 10 |
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| 22 |
24154510 | GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse. | 2013 Dec 15 |
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| 23 |
22768248 | Sensing of fatty acids for octanoylation of ghrelin involves a gustatory G-protein. | 2012 |
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| 24 |
22820510 | G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1. | 2012 Oct |
2 |
| 25 |
19369060 | Effects of long-term soluble vs. insoluble dietary fiber intake on high-fat diet-induced obesity in C57BL/6J mice. | 2010 Apr |
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| 26 |
20573884 | Taste preference for fatty acids is mediated by GPR40 and GPR120. | 2010 Jun 23 |
3 |
| 27 |
19720802 | Deletion of GPR40 impairs glucose-induced insulin secretion in vivo in mice without affecting intracellular fuel metabolism in islets. | 2009 Nov |
2 |
| 28 |
18559658 | The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. | 2008 Sep |
2 |
| 29 |
18617622 | Modulation of osteoclastogenesis by fatty acids. | 2008 Nov |
2 |
| 30 |
18678612 | Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease. | 2008 Nov |
4 |
| 31 |
17395749 | GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. | 2007 Apr |
3 |
| 32 |
17500511 | Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists. | 2007 Jun 14 |
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| 33 |
16267104 | Mouse GPR40 heterologously expressed in Xenopus oocytes is activated by short-, medium-, and long-chain fatty acids. | 2006 Mar |
2 |
| 34 |
16702987 | Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. | 2006 Jul |
2 |
| 35 |
16044321 | Free fatty acid receptor 1 (FFA(1)R/GPR40) and its involvement in fatty-acid-stimulated insulin secretion. | 2005 Nov |
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