Sorafenib

MET proto-oncogene, receptor tyrosine kinase ; Homo sapiens







21 Article(s)
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1 35546143 TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC. 2022 May 11 1
2 34076978 Long noncoding RNA NEAT1 aggravates sorafenib-resistance in non-small cell lung cancer via regulating miRNA-335/c-Met. 2021 Mar-Apr 6
3 32504550 Neratinib decreases pro-survival responses of [sorafenib + vorinostat] in pancreatic cancer. 2020 Aug 1
4 33014851 The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model. 2020 1
5 30647407 Activation of c-Met in cancer cells mediates growth-promoting signals against oxidative stress through Nrf2-HO-1. 2019 Jan 15 4
6 29552141 Synergistic antitumor activity of low-dose c-Met tyrosine kinase inhibitor and sorafenib on human non-small cell lung cancer cells. 2018 Apr 3
7 27849399 New chemical treatment options in second-line hepatocellular carcinoma: what to do when sorafenib fails? 2017 Jan 1
8 28164434 Dual inhibition of Akt and c-Met as a second-line therapy following acquired resistance to sorafenib in hepatocellular carcinoma cells. 2017 Mar 7
9 26790028 Elevated hepatocyte growth factor expression as an autocrine c-Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells. 2016 Apr 5
10 27203677 Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma. 2016 Jun 21 1
11 27896243 Profile of tivantinib and its potential in the treatment of hepatocellular carcinoma: the evidence to date. 2016 1
12 25668362 Clinical observation of liver cancer patients treated with axitinib and cabozantinib after failed sorafenib treatment: a case report and literature review. 2015 1
13 25862849 Sorafenib inhibits migration and invasion of hepatocellular carcinoma cells through suppression of matrix metalloproteinase expression. 2015 Apr 1
14 25895026 Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma. 2015 May 20 1
15 25057499 Hepatic stellate cell coculture enables sorafenib resistance in Huh7 cells through HGF/c-Met/Akt and Jak2/Stat3 pathways. 2014 2
16 23552472 Expression and prognostic value of VEGFR-2, PDGFR-β, and c-Met in advanced hepatocellular carcinoma. 2013 Apr 3 1
17 23680714 Advanced unresectable hepatocellular carcinoma: new biologics as fresh ammunition or clues to disease understanding? 2013 Jul 1
18 24330766 Effects of miR-193a and sorafenib on hepatocellular carcinoma cells. 2013 Dec 13 1
19 21734462 c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition. 2011 Sep 15 4
20 20432459 Involvement of receptor tyrosine phosphatase DEP-1 mediated PI3K-cofilin signaling pathway in sorafenib-induced cytoskeletal rearrangement in hepatoma cells. 2010 Aug 1
21 19220580 Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. 2009 Aug 4