Pub. Date : 2009 Aug
PMID : 19220580
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Sorafenib-induced phosphorylation of c-met, p70S6K and 4EBP1 was significantly reduced when 10-0505 cells were co-treated with anti-human anti-HGF antibody, suggesting that treatment with sorafenib leads to increased HGF secretion and activation of c-met and mTOR targets. | Sorafenib | MET proto-oncogene, receptor tyrosine kinase | Homo sapiens |
2 | Sorafenib-induced phosphorylation of c-met, p70S6K and 4EBP1 was significantly reduced when 10-0505 cells were co-treated with anti-human anti-HGF antibody, suggesting that treatment with sorafenib leads to increased HGF secretion and activation of c-met and mTOR targets. | Sorafenib | MET proto-oncogene, receptor tyrosine kinase | Homo sapiens |
3 | Sorafenib-induced phosphorylation of c-met, p70S6K and 4EBP1 was significantly reduced when 10-0505 cells were co-treated with anti-human anti-HGF antibody, suggesting that treatment with sorafenib leads to increased HGF secretion and activation of c-met and mTOR targets. | Sorafenib | MET proto-oncogene, receptor tyrosine kinase | Homo sapiens |
4 | Sorafenib-induced phosphorylation of c-met, p70S6K and 4EBP1 was significantly reduced when 10-0505 cells were co-treated with anti-human anti-HGF antibody, suggesting that treatment with sorafenib leads to increased HGF secretion and activation of c-met and mTOR targets. | Sorafenib | MET proto-oncogene, receptor tyrosine kinase | Homo sapiens |