| 1 |
34562242 | Imaging of the Ciliary Cholesterol Underlying the Sonic Hedgehog Signal Transduction. | 2022 |
2 |
| 2 |
35059566 | Identifying Molecular Fragments That Drive 7-Dehydrocholesterol Elevation. | 2022 Jan 14 |
2 |
| 3 |
35552960 | SQLE inhibition suppresses the development of pancreatic ductal adenocarcinoma and enhances its sensitivity to chemotherapeutic agents in vitro. | 2022 May 12 |
1 |
| 4 |
33284321 | Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway. | 2021 Jan 4 |
1 |
| 5 |
33422461 | Endothelial cells control vascular smooth muscle cell cholesterol levels by regulating 24-dehydrocholesterol reductase expression. | 2021 Feb 15 |
1 |
| 6 |
33671529 | Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence. | 2021 Feb 22 |
1 |
| 7 |
33681590 | Altered Cholesterol Biosynthesis Affects Drug Metabolism. | 2021 Mar 2 |
2 |
| 8 |
33741398 | An intronic DHCR7 genetic polymorphism associates with vitamin D serum level and incidence of acute coronary syndrome. | 2021 May |
2 |
| 9 |
33890232 | Anthropometric characteristics of 65 Polish Smith-Lemli-Opitz patients. | 2021 Sep |
1 |
| 10 |
34349606 | A Case of Smith-Lemli-Opitz Syndrome Diagnosed with Hypertrophic Pyloric Stenosis. | 2021 |
1 |
| 11 |
34440098 | Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context. | 2021 Jul 26 |
1 |
| 12 |
34726809 | Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling. | 2021 Dec |
1 |
| 13 |
31882361 | Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection. | 2020 Jan 14 |
1 |
| 14 |
31934493 | Disruption of Dhcr7 and Insig1/2 in cholesterol metabolism causes defects in bone formation and homeostasis through primary cilium formation. | 2020 |
2 |
| 15 |
32694168 | TMEM147 interacts with lamin B receptor, regulates its localization and levels, and affects cholesterol homeostasis. | 2020 Aug 21 |
1 |
| 16 |
33204589 | Familial DHCR7 genotype presenting as a very mild form of Smith-Lemli-Opitz syndrome and lethal holoprosencephaly. | 2020 Nov |
4 |
| 17 |
30535733 | Subcellular localization of sterol biosynthesis enzymes. | 2019 Feb |
1 |
| 18 |
30796319 | Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis. | 2019 Feb 22 |
2 |
| 19 |
31005410 | The Smith-Lemli-Opitz syndrome and dentofacial anomalies diagnostic: Case reports and literature review. | 2019 Jun |
1 |
| 20 |
31470109 | UV increases skin-derived 1α,25-dihydroxyvitamin D3 production, leading to MMP-1 expression by altering the balance of vitamin D and cholesterol synthesis from 7-dehydrocholesterol. | 2019 Dec |
4 |
| 21 |
31476115 | Small Molecule Antipsychotic Aripiprazole Potentiates Ozone-Induced Inflammation in Airway Epithelium. | 2019 Oct 21 |
3 |
| 22 |
29300326 | Computational Investigation of the Missense Mutations in DHCR7 Gene Associated with Smith-Lemli-Opitz Syndrome. | 2018 Jan 4 |
2 |
| 23 |
29352199 | Prevention of Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome. | 2018 Jan 19 |
3 |
| 24 |
29455191 | Smith-Lemli-Opitz syndrome: clinical and biochemical correlates. | 2018 Mar 28 |
1 |
| 25 |
29698737 | Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis. | 2018 Jun 15 |
1 |
| 26 |
29920211 | The combination of single nucleotide polymorphisms rs6720173 (ABCG5), rs3808607 (CYP7A1), and rs760241 (DHCR7) is associated with differing serum cholesterol responses to dairy consumption. | 2018 Oct |
1 |
| 27 |
30360379 | Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention. | 2018 Oct 22 |
1 |
| 28 |
26976653 | Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients. | 2017 May |
2 |
| 29 |
27520299 | Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis. | 2017 Jan |
4 |
| 30 |
28202290 | Effect of psychotropic drug treatment on sterol metabolism. | 2017 Sep |
1 |
| 31 |
26685159 | Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome. | 2016 Feb 15 |
1 |
| 32 |
26887953 | Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis. | 2016 Apr 15 |
7 |
| 33 |
26919959 | Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis. | 2016 Jun |
1 |
| 34 |
26959888 | Germline genetics of cancer of unknown primary (CUP) and its specific subtypes. | 2016 Apr 19 |
1 |
| 35 |
26998835 | Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes. | 2016 Apr |
1 |
| 36 |
27052530 | Common Variants in Cholesterol Synthesis- and Transport-Related Genes Associate with Circulating Cholesterol Responses to Intakes of Conventional Dairy Products in Healthy Individuals. | 2016 May |
4 |
| 37 |
27401223 | Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review. | 2016 Oct |
1 |
| 38 |
27697512 | DHCR7: A vital enzyme switch between cholesterol and vitamin D production. | 2016 Oct |
7 |
| 39 |
25040602 | Characterization of large deletions in the DHCR7 gene. | 2015 Aug |
1 |
| 40 |
25500071 | Rapid suppression of 7-dehydrocholesterol reductase activity in keratinocytes by vitamin D. | 2015 Apr |
1 |
| 41 |
25637936 | The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally. | 2015 Apr |
2 |
| 42 |
26350811 | Varying relationship between 25-hydroxy-vitamin D, high density lipoprotein cholesterol, and serum 7-dehydrocholesterol reductase with sunlight exposure. | 2015 Sep-Oct |
2 |
| 43 |
24158702 | Molecular pathways: sterols and receptor signaling in cancer. | 2014 Jan 1 |
2 |
| 44 |
24861183 | Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. | 2014 |
1 |
| 45 |
24907491 | MicroRNAs: a connection between cholesterol metabolism and neurodegeneration. | 2014 Dec |
3 |
| 46 |
24950029 | Serum lipoprotein composition and vitamin D metabolite levels in clinically isolated syndromes: Results from a multi-center study. | 2014 Sep |
1 |
| 47 |
25048193 | The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis. | 2014 Oct |
4 |
| 48 |
25117108 | Fresh frozen plasma as a source of cholesterol for newborn with Smith-Lemli-Opitz syndrome associated with defective cholesterol synthesis. | 2014 Summer |
1 |
| 49 |
25272525 | [Smith-Lemli-Opitz syndrome and hypothyroidism: the first Venezuelan case]. | 2014 Sep |
1 |
| 50 |
22929031 | Maternal ABCA1 genotype is associated with severity of Smith-Lemli-Opitz syndrome and with viability of patients homozygous for null mutations. | 2013 Mar |
1 |