Title : Identification of Environmental Quaternary Ammonium Compounds as Direct Inhibitors of Cholesterol Biosynthesis.

Pub. Date : 2016 Jun

PMID : 26919959






1 Functional Relationships(s)
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1 We found that a common disinfectant mixture, benzalkonium chlorides (BACs), exhibits high potency in inhibiting DHCR7, as suggested by greatly elevated levels of the cholesterol precursor, 7-dehydrocholesterol (7-DHC). Cholesterol 7-dehydrocholesterol reductase Homo sapiens