dsbs

RAD50 double strand break repair protein ; Homo sapiens







18 Article(s)
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1 35076389 Structure of the human ATM kinase and mechanism of Nbs1 binding. 2022 Jan 25 1
2 31231660 Processing of DNA Double-Strand Breaks by the MRX Complex in a Chromatin Context. 2019 1
3 26743002 S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex. 2016 Mar 18 1
4 26951044 Targeting Rad50 sensitizes human nasopharyngeal carcinoma cells to radiotherapy. 2016 Mar 7 1
5 24642965 RAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapy. 2014 Jun 1 1
6 25213441 ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends. 2014 Dec 1
7 23912341 Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms. 2013 Dec 20 1
8 22131123 Impact of heterozygous c.657-661del, p.I171V and p.R215W mutations in NBN on nibrin functions. 2012 May 1
9 21150274 ATM activation in the presence of oxidative stress. 2010 Dec 15 1
10 21290468 Hyperthermia alters the interaction of proteins of the Mre11 complex in irradiated cells. 2010 Oct 1
11 20064462 CtIP links DNA double-strand break sensing to resection. 2009 Dec 25 1
12 18632984 Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex. 2008 Sep 1
13 16879433 Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation. 2006 Aug 2
14 15908798 The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. 2005 Jun 1
15 14532133 Requirement of the MRN complex for ATM activation by DNA damage. 2003 Oct 15 1
16 14657032 The Mre11 complex is required for ATM activation and the G2/M checkpoint. 2003 Dec 15 1
17 11832209 The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. 2002 Jan 25 1
18 11533665 Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. 2001 Sep 1