firibastat

glutamyl aminopeptidase ; Homo sapiens







12 Article(s)
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1 35163378 Current Knowledge about the New Drug Firibastat in Arterial Hypertension. 2022 Jan 27 1
2 33520782 Firibastat, the first-in-class brain aminopeptidase a inhibitor, in the management of hypertension: A review of clinical trials. 2021 Jan-Mar 2
3 33683322 Brain ACE2 activation following brain aminopeptidase A blockade by firibastat in salt-dependent hypertension. 2021 Mar 26 1
4 33881611 Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brain. 2021 Jun 1
5 32955085 Structural insight into the catalytic mechanism and inhibitor binding of aminopeptidase A. 2020 Nov 13 2
6 30882604 A pilot double-blind randomized placebo-controlled crossover pharmacodynamic study of the centrally active aminopeptidase A inhibitor, firibastat, in hypertension. 2019 Aug 2
7 31014072 Efficacy and Safety of Firibastat, A First-in-Class Brain Aminopeptidase A Inhibitor, in Hypertensive Overweight Patients of Multiple Ethnic Origins. 2019 Jul 9 1
8 24337978 Randomised, double-blind, placebo-controlled, dose-escalating phase I study of QGC001, a centrally acting aminopeptidase a inhibitor prodrug. 2014 Apr 1
9 25474003 [Orally active aminopeptidase A inhibitors reduce blood pressure: a new strategy for treating hypertension]. 2014 1
10 21763394 The role of the brain renin-angiotensin system in hypertension: implications for new treatment. 2011 Oct 1
11 18175217 Aminopeptidase A inhibitors as centrally acting antihypertensive agents. 2008 Sep 1
12 15748538 Role of angiotensin III in hypertension. 2005 Apr 1