Title : Brain ACE2 activation following brain aminopeptidase A blockade by firibastat in salt-dependent hypertension.

Pub. Date : 2021 Mar 26

PMID : 33683322






1 Functional Relationships(s)
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1 RB150/firibastat treatment constitutes an interesting therapeutic approach to improve BP control in hypertensive patients by inducing in the brain renin-angiotensin system, hyperactivity of the beneficial ACE2/Ang 1-7/MasR axis while decreasing that of the deleterious APA/Ang II/Ang III/ATI receptor axis. firibastat glutamyl aminopeptidase Homo sapiens