Polyamines

MYCN proto-oncogene, bHLH transcription factor ; Homo sapiens







13 Article(s)
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1 35174317 MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma. 2022 Feb 1
2 33918978 A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma. 2021 Apr 9 1
3 34129075 Probenecid increases renal retention and antitumor activity of DFMO in neuroblastoma. 2021 Oct 1
4 32786875 Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells. 2020 Aug 28 1
5 25593318 Polyamine metabolism is sensitive to glycolysis inhibition in human neuroblastoma cells. 2015 Mar 6 2
6 26835380 Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma. 2015 Jul 1
7 25426416 MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines. 2014 2
8 23440295 DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma. 2013 Apr 1
9 23457004 AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport. 2013 Sep 15 1
10 19960435 The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification. 2010 May 1 1
11 19147568 Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma. 2009 Jan 15 1
12 19584241 Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma. 2009 Jul 1
13 16007177 Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells. 2005 Aug 25 2