Title : MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma.

Pub. Date : 2022 Feb

PMID : 35174317






1 Functional Relationships(s)
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1 In addition, MYCN-amplified NB tumors have high levels of methylthioadenosine phosphorylase (MTAP), an enzyme that helps salvage methionine following polyamine metabolism. Polyamines MYCN proto-oncogene, bHLH transcription factor Homo sapiens