Ceramides

nuclear factor kappa B subunit 1 ; Homo sapiens







47 Article(s)
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1 33612070 NF-κB pathway play a role in SCD1 deficiency-induced ceramide de novo synthesis. 2021 Feb 1 2
2 32222879 Ceramide and palmitic acid inhibit macrophage-mediated epithelial-mesenchymal transition in colorectal cancer. 2020 May 1
3 26807955 Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway. 2016 1
4 24876379 The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1. 2014 Jul 25 1
5 23065519 Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets. 2013 May 2
6 21984552 Short-term magnesium deficiency upregulates ceramide synthase in cardiovascular tissues and cells: cross-talk among cytokines, Mg2+, NF-κB, and de novo ceramide. 2012 Jan 1 1
7 23042913 Increased ceramide content and NFκB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males. 2012 Dec 1 1
8 22065582 Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression. 2011 Dec 30 1
9 17944019 Surfactant "fortification" by topical inhibition of nuclear factor-kappaB activity in a newborn piglet lavage model. 2007 Oct 2
10 15901738 Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells. 2005 Jul 15 1
11 15161907 beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappaB but potentiates apoptosis. 2004 Aug 6 1
12 15322180 Ceramide inhibits IL-2 production by preventing protein kinase C-dependent NF-kappaB activation: possible role in protein kinase Ctheta regulation. 2004 Sep 1 7
13 14609747 Oleandrin suppresses activation of nuclear transcription factor-kappa B and activator protein-1 and potentiates apoptosis induced by ceramide. 2003 Dec 1 3
14 14760934 Regulation of nuclear factor-kappaB in intestinal epithelial cells in a cell model of inflammation. 2003 Oct 1
15 14995068 Differential involvement of ceramide in TNFalpha-mediated activation of NF-kappaB in primary human keratinocytes and HaCaT keratinocytes. 2003 4
16 12208496 Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells. 2002 Aug 28 3
17 12395108 Regulation of nociceptin/orphanin FQ gene expression in astrocytes by ceramide. 2002 Oct 7 3
18 12444159 Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. 2002 Dec 1 1
19 11689465 Ceramide inhibition of NF-kappaB activation involves reverse translocation of classical protein kinase C (PKC) isoenzymes: requirement for kinase activity and carboxyl-terminal phosphorylation of PKC for the ceramide response. 2001 Nov 4
20 11698477 Ceramide regulates lipopolysaccharide-induced phosphatidylinositol 3-kinase and Akt activity in human alveolar macrophages. 2001 Nov 15 1
21 10788436 Protein tyrosine kinase p56lck is required for ceramide-induced but not tumor necrosis factor-induced activation of NF-kappa B, AP-1, JNK, and apoptosis. 2000 May 5 1
22 10954916 Bcl-x(L) suppresses TNF-mediated apoptosis and activation of nuclear factor-kappaB, activation protein-1, and c-Jun N-terminal kinase. 2000 Aug 1
23 10964614 Ceramide initiates NFkappaB-mediated caspase activation in neuronal apoptosis. 2000 Aug 3
24 11062012 Ceramide induction of COX-2 and PGE(2) in pulmonary A549 cells does not involve activation of NF-kappaB. 2000 Nov 2 1
25 10075082 Suppression of tumor necrosis factor-activated nuclear transcription factor-kappaB, activator protein-1, c-Jun N-terminal kinase, and apoptosis by beta-lapachone. 1999 Apr 1 1
26 10348816 Helicobacter pylori-dependent ceramide production may mediate increased interleukin 8 expression in human gastric cancer cell lines. 1999 Jun 1
27 10486254 Ceramide synergizes with phorbol ester or okadaic acid to induce IkappaB degradation. 1999 Sep 16 2
28 9582369 Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1. 1998 May 22 1
29 9593751 Constitutive activation of NF-kappaB causes resistance to apoptosis in human cutaneous T cell lymphoma HuT-78 cells. Autocrine role of tumor necrosis factor and reactive oxygen intermediates. 1998 May 29 1
30 9616231 Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells. 1998 Jun 1 1
31 9624136 Ceramide activates NFkappaB by inducing the processing of p105. 1998 Jun 19 6
32 9743347 IL-13 suppresses TNF-induced activation of nuclear factor-kappa B, activation protein-1, and apoptosis. 1998 Sep 15 1
33 9743348 Alpha-melanocyte-stimulating hormone inhibits the nuclear transcription factor NF-kappa B activation induced by various inflammatory agents. 1998 Sep 15 1
34 9148901 Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells. 1997 May 16 1
35 9195956 Selective involvement of ceramide in cytokine-induced apoptosis. Ceramide inhibits phorbol ester activation of nuclear factor kappaB. 1997 Jun 27 5
36 9335256 Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. 1997 Sep 15 1
37 8674577 Activation of NF kappa B and potentiation of TNF-induced NF kappa B activation by ceramide analogues in leukemic cell lines despite the absence of an observed sphingomyelinase signalling event. 1996 Feb 2
38 8683130 Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation. 1996 Jul 1 2
39 7738000 Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B. 1995 May 5 1
40 8530143 TNF-induced activation of NF-kappa B. 1995 Jul 4
41 7929233 Reconstitution of nuclear factor kappa B activation induced by tumor necrosis factor requires membrane-associated components. Comparison with pathway activated by ceramide. 1994 Oct 14 3
42 8132572 Dissociation of endogenous cellular ceramide from NF-kappa B activation. 1994 Mar 18 1
43 8188652 Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system. 1994 May 13 1
44 8207213 Inhibition of ceramide pathway does not affect ability of TNF-alpha to activate nuclear factor-kappa B. 1994 Jun 15 8
45 8349660 Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B. 1993 Aug 25 1
46 8376408 Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells. 1993 Sep 25 1
47 1330325 TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. 1992 Nov 27 1