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28881286 | Synthesis and evaluation of asymmetric curcuminoid analogs as potential anticancer agents that downregulate NF-κB activation and enhance the sensitivity of gastric cancer cell lines to irinotecan chemotherapy. | 2017 Oct 20 |
1 |
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26431797 | CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings. | 2015 Dec 1 |
1 |
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22791234 | Phase II 2-arm trial of the proteasome inhibitor, PS-341 (bortezomib) in combination with irinotecan or PS-341 alone followed by the addition of irinotecan at time of progression in patients with locally recurrent or metastatic squamous cell carcinoma of the head and neck (E1304): a trial of the Eastern Cooperative Oncology Group. | 2013 Jul |
1 |
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23348635 | Concurrent chemotherapy inhibits herpes simplex virus-1 replication and oncolysis. | 2013 Feb |
1 |
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22206574 | Multi-tyrosine kinase inhibitors in preclinical studies for pediatric CNS AT/RT: Evidence for synergy with Topoisomerase-I inhibition. | 2011 Dec 29 |
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21472350 | Establishment and characterization of irinotecan-resistant human non-small cell lung cancer A549 cells. | 2010 Nov-Dec |
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18182997 | Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells. | 2008 Jan 29 |
5 |
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18347181 | Irinotecan pharmacogenetics: influence of pharmacodynamic genes. | 2008 Mar 15 |
1 |
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15809721 | Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells. | 2005 May |
5 |
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15275881 | Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer. | 2004 Aug |
2 |
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11691793 | Activation of nuclear factor kappaB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells. | 2001 Nov 1 |
2 |
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10811101 | Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. | 2000 May 1 |
4 |
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10202930 | Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. | 1999 Apr |
2 |