Genistein

nuclear factor kappa B subunit 1 ; Homo sapiens







72 Article(s)
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1 35140617 Genistein: A Review on its Anti-Inflammatory Properties. 2022 2
2 33749495 The second phase of brain trauma can be controlled by nutraceuticals that suppress DAMP-mediated microglial activation. 2021 May 1
3 34521933 Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations. 2021 Sep 14 1
4 30743203 Genistein suppresses psoriasis-related inflammation through a STAT3-NF-κB-dependent mechanism in keratinocytes. 2019 Apr 3
5 30897972 Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy. 2019 Jan-Dec 1
6 31359993 Molecular docking analysis of nuclear factor-κB and genistein interaction in the context of breast cancer. 2019 1
7 31610186 Flavonoids reduces lipopolysaccharide-induced release of inflammatory mediators in human bronchial epithelial cells: Structure-activity relationship. 2019 Dec 15 1
8 29344275 Genistein Promotes Proliferation of Human Cervical Cancer Cells Through Estrogen Receptor-Mediated PI3K/Akt-NF-κB Pathway. 2018 3
9 28259980 Genistein decreases A549 cell viability via inhibition of the PI3K/AKT/HIF‑1α/VEGF and NF‑κB/COX‑2 signaling pathways. 2017 Apr 2
10 28627607 Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4'-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity. 2017 Aug 1
11 29202800 Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway. 2017 Dec 4 4
12 26718793 Genistein inhibits the proliferation of human multiple myeloma cells through suppression of nuclear factor-κB and upregulation of microRNA-29b. 2016 Feb 5
13 27035424 Effects of resveratrol and genistein on nuclear factor‑κB, tumor necrosis factor‑α and matrix metalloproteinase‑9 in patients with chronic obstructive pulmonary disease. 2016 May 1
14 24491678 Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia. 2014 Apr 5 3
15 24606736 [Effect of genistein on the TLR and MAPK transduction cascades in lipopolysaccharide -stimulated macrophages]. 2014 Mar 1
16 24669186 Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. 2014 2
17 24742714 Genistein inhibits phorbol ester-induced NF-κB transcriptional activity and COX-2 expression by blocking the phosphorylation of p65/RelA in human mammary epithelial cells. 2014 Oct 2
18 25128065 Apoptotic effect of genistein on human colon cancer cells via inhibiting the nuclear factor-kappa B (NF-κB) pathway. 2014 Nov 2
19 25447760 Anti-inflammatory effect of gamma-irradiated genistein through inhibition of NF-κB and MAPK signaling pathway in lipopolysaccharide-induced macrophages. 2014 Dec 1
20 23267126 Genistein and daidzein: different molecular effects on prostate cancer. 2013 Jan 1
21 23365634 Genistein sensitizes bladder cancer cells to HCPT treatment in vitro and in vivo via ATM/NF-κB/IKK pathway-induced apoptosis. 2013 3
22 23661994 Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105. 2013 Jan 1
23 22284780 Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. 2012 Jan 2
24 22387535 Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: suppression of serine/threonine and tyrosine kinases. 2012 May 15 2
25 23056046 Sensitization of Cervical Cancer Cells to Cisplatin by Genistein: The Role of NFκB and Akt/mTOR Signaling Pathways. 2012 2
26 20107864 A phase II study of isoflavones, erlotinib, and gemcitabine in advanced pancreatic cancer. 2011 Aug 1
27 21078540 Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB. 2011 Feb 1 4
28 21965740 Phytoestrogens induce apoptosis via extrinsic pathway, inhibiting nuclear factor-kappaB signaling in HER2-overexpressing breast cancer cells. 2011 Oct 1
29 22289529 Involvement of nuclear factor κB (NF-κB) in the downregulation of cyclooxygenase-2 (COX-2) by genistein in gastric cancer cells. 2011 5
30 20038829 Enhanced anticancer effect of gemcitabine by genistein in osteosarcoma: the role of Akt and nuclear factor-kappaB. 2010 Mar 2
31 20225658 The effects of genistein and puerarin on the activation of nuclear factor-kappaB and the production of tumor necrosis factor-alpha in asthma patients. 2010 Feb 7
32 19086989 Genistein reverses diminished T-cell signal transduction, induced by post-menopausal estrogen levels. 2009 Jan 1
33 19107739 Genistein down-regulates the constitutive activation of nuclear factor-kappaB in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. 2009 Jun 6
34 19288574 Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines. 2009 May 15 3
35 18471101 Aquatic birnavirus infection activates the transcription factor NF-kappaB via tyrosine kinase signalling leading to cell death. 2008 Jun 2
36 18761399 Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway. 2008 Oct 6
37 17052999 Complementary actions of docosahexaenoic acid and genistein on COX-2, PGE2 and invasiveness in MDA-MB-231 breast cancer cells. 2007 Apr 2
38 17131310 In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. 2007 Feb 15 3
39 17404287 A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein. 2007 Apr 15 6
40 16284950 Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells. 2006 Apr 15 3
41 16452247 Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis. 2006 Feb 1 1
42 16475211 Cisplatin-induced antitumor activity is potentiated by the soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts. 2006 Mar 15 4
43 16613577 The role of genistein and synthetic derivatives of isoflavone in cancer prevention and therapy. 2006 Apr 2
44 16640785 Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. 2006 Apr 26 4
45 16873071 Estrogen dependent growth inhibitory effects of tamoxifen but not genistein in solid tumors derived from estrogen receptor positive (ER+) primary breast carcinoma MCF7: single agent and novel combined treatment approaches. 2006 Jul 1
46 16966488 Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: involvement of estrogen receptors, ERK1/2, and NFkappaB. 2006 Oct 1
47 17079479 Potentiation of the effect of erlotinib by genistein in pancreatic cancer: the role of Akt and nuclear factor-kappaB. 2006 Nov 1 1
48 15992833 Modulation of signal transduction by tea catechins and related phytochemicals. 2005 Dec 11 1
49 16061678 Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. 2005 Aug 1 5
50 16195219 Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappaB, and serine and tyrosine phosphorylation of IkappaB-alpha in lipopolysaccharide-stimulated raw 264.7 macrophages. 2005 Oct 8 2