Title : Double-edged sword effect of biochanin to inhibit nuclear factor kappaB: suppression of serine/threonine and tyrosine kinases.

Pub. Date : 2012 May 15

PMID : 22387535






2 Functional Relationships(s)
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1 In this study I found that biochanin, a methoxy form of genistein, inhibits IL-8-mediated activation of nuclear transcription factor kappaB (NF-kappaB) and activator protein 1 (AP-1) more potently than genistein as shown in Jurkat T-cell line. Genistein nuclear factor kappa B subunit 1 Homo sapiens
2 In this study I found that biochanin, a methoxy form of genistein, inhibits IL-8-mediated activation of nuclear transcription factor kappaB (NF-kappaB) and activator protein 1 (AP-1) more potently than genistein as shown in Jurkat T-cell line. Genistein nuclear factor kappa B subunit 1 Homo sapiens