| 1 |
35164193 | Enhanced Enzyme Reuse through the Bioconjugation of L-Asparaginase and Silica-Based Supported Ionic Liquid-like Phase Materials. | 2022 Jan 29 |
2 |
| 2 |
35205650 | Novel Insights on the Use of L-Asparaginase as an Efficient and Safe Anti-Cancer Therapy. | 2022 Feb 11 |
1 |
| 3 |
32707027 | Optimization, Purification and Antitumor Activity of Kodamaea ohmeri ANOMY L-Asparaginase Isolated from Banana Peel. | 2021 |
2 |
| 4 |
33615182 | Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms. | 2021 Feb 12 |
4 |
| 5 |
33685385 | A Patent Review on the Use of L-Asparaginase in the Treatment of Acute Lymphocytic Leukemia. | 2021 |
1 |
| 6 |
33911966 | Production, purification, characterization, antioxidant and antiproliferative activities of extracellular L-asparaginase produced by Fusarium equiseti AHMF4. | 2021 Apr |
2 |
| 7 |
34076169 | Studies on the recombinant production and anticancer activity of thermostable L- asparaginase I from Pyrococcus abyssi. | 2021 |
1 |
| 8 |
34249720 | ASRGL1 Correlates With Immune Cell Infiltration in Hepatocellular Carcinoma and Can Serve as a Prognostic Biomarker. | 2021 |
2 |
| 9 |
34728685 | Superior operational stability of immobilized L-asparaginase over surface-modified carbon nanotubes. | 2021 Nov 2 |
2 |
| 10 |
30823860 | Pegaspargase-induced hypertriglyceridemia in a patient with acute lymphoblastic leukemia. | 2020 Jan |
2 |
| 11 |
32180807 | Development and Validation of a Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry Method for the Determination of Asparagine in Human Serum. | 2020 |
6 |
| 12 |
32268116 | ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. | 2020 Apr 7 |
1 |
| 13 |
32434038 | The role of the quaternary structure in the activation of human L-asparaginase. | 2020 Jul 30 |
2 |
| 14 |
33117129 | L-Asparaginase Exerts Neuroprotective Effects in an SH-SY5Y-A53T Model of Parkinson's Disease by Regulating Glutamine Metabolism. | 2020 |
1 |
| 15 |
30727907 | Polyethylene Glycol Acts as a Mechanistic Stabilizer of L-asparaginase: A Computational Probing. | 2019 |
3 |
| 16 |
30920200 | Enzyme Reactor Based on Reversible pH-Controlled Catalytic Polymer Porous Membrane. | 2019 Apr 24 |
1 |
| 17 |
30993718 | Bacterial l-asparaginases for cancer therapy: Current knowledge and future perspectives. | 2019 Nov |
1 |
| 18 |
31209181 | Glutaminase Activity of L-Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia. | 2019 Sep |
1 |
| 19 |
29316436 | Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. | 2018 Jan 8 |
1 |
| 20 |
29343523 | A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo. | 2018 Mar 15 |
1 |
| 21 |
29767260 | RNAi‑mediated downregulation of asparaginase‑like protein 1 inhibits growth and promotes apoptosis of human cervical cancer line SiHa. | 2018 Jul |
2 |
| 22 |
29878070 | Optimization of a Precolumn OPA Derivatization HPLC Assay for Monitoring of l-Asparagine Depletion in Serum during l-Asparaginase Therapy. | 2018 Oct 1 |
2 |
| 23 |
29966654 | l-asparaginase induces intrinsic mitochondrial-mediated apoptosis in human gastric adenocarcinoma cells and impedes tumor progression. | 2018 Sep 18 |
3 |
| 24 |
30155702 | A critical analysis of L-asparaginase activity quantification methods-colorimetric methods versus high-performance liquid chromatography. | 2018 Nov |
2 |
| 25 |
28245869 | Regulation of stem-like cancer cells by glutamine through β-catenin pathway mediated by redox signaling. | 2017 Feb 28 |
1 |
| 26 |
28424408 | Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer. | 2017 Jun 27 |
1 |
| 27 |
28671681 | Extracellular vesicles are independent metabolic units with asparaginase activity. | 2017 Sep |
1 |
| 28 |
29299118 | Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase. | 2017 Dec 15 |
3 |
| 29 |
30023574 | Agro Waste Utilization for Cost-Effective Production of l-Asparaginase by Pseudomonas plecoglossicida RS1 with Anticancer and Acrylamide Mitigation Potential. | 2017 Nov 30 |
1 |
| 30 |
26239197 | Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells. | 2016 Jan |
2 |
| 31 |
26672444 | Amino acid residues adjacent to the catalytic cavity of tetramer L-asparaginase II contribute significantly to its catalytic efficiency and thermostability. | 2016 Jan |
1 |
| 32 |
26780688 | Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages. | 2016 Feb 16 |
2 |
| 33 |
26878238 | Tumour-specific proline vulnerability uncovered by differential ribosome codon reading. | 2016 Feb 25 |
1 |
| 34 |
27106100 | A missense mutation in ASRGL1 is involved in causing autosomal recessive retinal degeneration. | 2016 Jun 15 |
1 |
| 35 |
27452168 | Solid-State Fermentation vs Submerged Fermentation for the Production of l-Asparaginase. | 2016 |
2 |
| 36 |
27770857 | Marine Microorganism: An Underexplored Source of l-Asparaginase. | 2016 |
1 |
| 37 |
27866936 | Current applications and different approaches for microbial l-asparaginase production. | 2016 Dec |
2 |
| 38 |
28330312 | Isolation and screening of L-asparaginase free of glutaminase and urease from fungal sp. | 2016 Dec |
2 |
| 39 |
25626693 | Differential mechanisms of asparaginase resistance in B-type acute lymphoblastic leukemia and malignant natural killer cell lines. | 2015 Jan 28 |
8 |
| 40 |
26178806 | Asparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis). | 2015 Sep |
4 |
| 41 |
26331698 | A clinically attainable dose of L-asparaginase targets glutamine addiction in lymphoid cell lines. | 2015 Nov |
1 |
| 42 |
24033105 | Expression of asparagine synthetase predicts in vitro response to L-asparaginase in canine lymphoid cell lines. | 2014 Jun |
2 |
| 43 |
24657844 | Human 60-kDa lysophospholipase contains an N-terminal L-asparaginase domain that is allosterically regulated by L-asparagine. | 2014 May 9 |
1 |
| 44 |
24702187 | Cerebrospinal fluid asparagine depletion during pegylated asparaginase therapy in children with acute lymphoblastic leukaemia. | 2014 Jul |
1 |
| 45 |
25112526 | Successful use of octreotide as a chemoprotectant for prevention of PEG-asparaginase-induced pancreatitis. | 2014 Aug |
1 |
| 46 |
25177232 | Targeted metabolomic analysis of amino acid response to L-asparaginase in adherent cells. | 2014 |
4 |
| 47 |
25242145 | Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion. | 2014 Oct 23 |
1 |
| 48 |
23161488 | Microchip CE-LIF method for the hydrolysis of L-glutamine by using L-asparaginase enzyme reactor based on gold nanoparticle. | 2013 Feb |
3 |
| 49 |
23398626 | A rapid, efficient and sensitive plate assay for detection and screening of l-asparaginase-producing microorganisms. | 2013 Apr |
1 |
| 50 |
23585457 | Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine. | 2013 May 15 |
2 |