Polyethylene Glycols

asparaginase and isoaspartyl peptidase 1 ; Homo sapiens







26 Article(s)
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1 30727907 Polyethylene Glycol Acts as a Mechanistic Stabilizer of L-asparaginase: A Computational Probing. 2019 4
2 30052638 Thiol-maleimide poly(ethylene glycol) crosslinking of L-asparaginase subunits at recombinant cysteine residues introduced by mutagenesis. 2018 1
3 28660740 Prolonged first-line PEG-asparaginase treatment in pediatric acute lymphoblastic leukemia in the NOPHO ALL2008 protocol-Pharmacokinetics and antibody formation. 2017 Dec 1
4 26695272 Asymmetrical flow field-flow fractionation for the analysis of PEG-asparaginase. 2016 1
5 25854457 [Safety of polyethylene glycol conjugated L-asparaginase in patients with acute lymphoblastic leukemia and T cell non-Hodgkin lymphoma]. 2015 Mar 2
6 24649212 A phase II clinical trial of polyethylene glycol-conjugated L-asparaginase in patients with advanced ovarian cancer: Early closure for safety. 2013 May 2
7 22888537 A PEGylation technology of L-asparaginase with monomethoxy polyethylene glycol-propionaldehyde. 2012 May-Jun 1
8 22042277 Polyethylene Glycol-conjugated L-asparaginase versus native L-asparaginase in combination with standard agents for children with acute lymphoblastic leukemia in second bone marrow relapse: a Children's Oncology Group Study (POG 8866). 2011 Dec 5
9 22312702 Formulation of PEG-ylated L-asparaginase loaded poly (lactide-co-glycolide) nanoparticles: influence of Pegylation on enzyme loading, activity and in vitro release. 2011 Dec 1
10 20007809 Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia. 2010 Feb 18 1
11 17226958 Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge. 2007 Jan-Feb 2
12 17551397 Intensified PEG-L-asparaginase and antimetabolite-based therapy for treatment of higher risk precursor-B acute lymphoblastic leukemia: a report from the Children's Oncology Group. 2007 Jun 2
13 15328169 Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia. 2004 Aug 15 1
14 12695020 Stabilisation and determination of the biological activity of L-asparaginase in poly(D,L-lactide-co-glycolide) nanospheres. 2003 Apr 30 1
15 12833461 A Phase I-II trial of polyethylene glycol-conjugated L-asparaginase in patients with multiple myeloma. 2003 Jul 1 5
16 12022502 Poly(hydroxybutyrate-co-hydroxyvalerate) nanocapsules as enzyme carriers for cancer therapy: an in vitro study. 2002 May-Jun 1
17 11221967 A phase I and pharmacodynamic evaluation of polyethylene glycol-conjugated L-asparaginase in patients with advanced solid tumors. 2001 3
18 10961868 Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: a Pediatric Oncology Group Study. 2000 Sep 1 1
19 10506705 Combination therapy with methotrexate, vincristine, polyethylene-glycol conjugated-asparaginase, and prednisone in the treatment of patients with refractory or recurrent acute lymphoblastic leukemia. 1999 Oct 1 4
20 9161659 Pegaspargase: an alternative? 1997 May 3
21 7850718 An open-label, multicenter study of polyethylene glycol-L-asparaginase for the treatment of acute lymphoblastic leukemia. 1995 Mar 1 2
22 1567419 Chemical modification of L-asparaginase with a comb-shaped copolymer of polyethylene glycol derivative and maleic anhydride. 1992 Apr 15 1
23 2345067 A phase II trial of PEG-L-asparaginase in the treatment of non-Hodgkins lymphoma. 1990 Feb 1
24 3210651 [Clinical experiences with polyethylene glycol-bound E. coli L-asparaginase in patients with multiple recurrences of acute lymphoblastic leukemia]. 1988 May-Jun 1
25 2872037 Clinical pharmacology of polyethylene glycol-L-asparaginase. 1986 May-Jun 2
26 4041512 Use of the polyethylene glycol adduct of L-asparaginase for the treatment of hyperasparaginemia in a schizophrenic patient. 1985 Oct 3