sphingosine 1-phosphate

sphingosine kinase 1 ; Mus musculus







58 Article(s)
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1 34865521 Impaired Sphingosine-1-Phosphate Synthesis Induces Preeclampsia by Deactivating Trophoblastic YAP (Yes-Associated Protein) Through S1PR2 (Sphingosine-1-Phosphate Receptor-2)-Induced Actin Polymerizations. 2022 Feb 1
2 35014213 Dual Targeting of Angipoietin-1 and von Willebrand Factor by microRNA-671-5p Attenuates Liver Angiogenesis and Fibrosis. 2022 Jun 2
3 33199821 Loss of sphingosine 1-phosphate receptor 3 gene function impairs injury-induced stromal angiogenesis in mouse cornea. 2021 Feb 2
4 33807180 Silencing of Sphingosine kinase 1 Affects Maturation Pathways in Mouse Neonatal Cardiomyocytes. 2021 Mar 31 2
5 33865856 A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells. 2021 Jan-Jun 2
6 34054552 Salidroside Inhibits CCl4-Induced Liver Fibrosis in Mice by Reducing Activation and Migration of HSC Induced by Liver Sinusoidal Endothelial Cell-Derived Exosomal SphK1. 2021 2
7 34109517 Blocking SphK1/S1P/S1PR1 Signaling Pathway Alleviates Lung Injury Caused by Sepsis in Acute Ethanol Intoxication Mice. 2021 Dec 2
8 34176100 Hyperoxia-induced S1P1 signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia. 2021 Sep 2
9 31838904 Cardiovascular Effects of Pharmacological Targeting of Sphingosine Kinase 1. 2020 Feb 4
10 32192225 Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts. 2020 Mar 17 2
11 32393187 Detrimental role of sphingosine kinase 1 in kidney damage in DOCA-salt hypertensive model: evidence from knockout mice. 2020 May 11 1
12 32738398 Generation of sphingosine-1-phosphate by sphingosine kinase 1 protects nonalcoholic fatty liver from ischemia/reperfusion injury through alleviating reactive oxygen species production in hepatocytes. 2020 Nov 1 1
13 30840833 Examination of the role of sphingosine kinase 2 in a murine model of systemic lupus erythematosus. 2019 Jun 1
14 30963819 Sphk1/S1P/S1PR1 Signaling is Involved in the Development of Autoimmune Thyroiditis in Patients and NOD.H-2h4 Mice. 2019 May 1
15 30997640 Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. 2019 Oct 1
16 31027910 Sphingosine kinase 1 knockout alleviates hepatic ischemia/reperfusion injury by attenuating inflammation and oxidative stress in mice. 2019 Jun 2
17 31412253 Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. 2019 Aug 13 2
18 31638192 Upregulation of sphingosine kinase 1 contributes to ventilator-associated lung injury in a two-hit model. 2019 Dec 1
19 29298188 Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2. 2018 Mar 2
20 29321954 A role for caspase-2 in sphingosine kinase 1 proteolysis in response to doxorubicin in breast cancer cells - implications for the CHK1-suppressed pathway. 2018 Jan 2
21 29392309 Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. 2018 Feb 1 1
22 29623068 Nuclear Insulin-Like Growth Factor Binding Protein-3 As a Biomarker in Triple-Negative Breast Cancer Xenograft Tumors: Effect of Targeted Therapy and Comparison With Chemotherapy. 2018 1
23 29662189 AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells. 2018 Jul 2
24 29673590 The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death. 2018 Jun 7 2
25 30463717 Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression. 2018 Dec 1
26 27799486 Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ. 2017 Apr 2
27 28583134 Sphingosine kinase 1 expression enhances colon tumor growth. 2017 Jun 6 2
28 28733250 Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy. 2017 Sep 2
29 29028945 Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis. 2017 Dec 7 2
30 26716409 Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer. 2016 Jan 26 4
31 26948947 Polydatin attenuates AGEs-induced upregulation of fibronectin and ICAM-1 in rat glomerular mesangial cells and db/db diabetic mice kidneys by inhibiting the activation of the SphK1-S1P signaling pathway. 2016 May 15 2
32 27547823 IL4RA on lymphatic endothelial cells promotes T cell egress during sclerodermatous graft versus host disease. 2016 Aug 4 1
33 27733910 Sphingosine kinase 1 inhibition improves lipopolysaccharide/D-galactosamine-induced acute liver failure by inhibiting mitogen-activated protein kinases pathway. 2016 Oct 2
34 25056275 Sphingosine-1-phosphate and its effect on glucose deprivation/glucose reload stress: from gene expression to neuronal survival. 2015 1
35 25587035 Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity. 2015 Mar 5 1
36 26129975 Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. 2015 Jul 31 1
37 26701909 TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. 2015 Dec 23 1
38 24473437 Sphingosine kinase 1 regulates adipose proinflammatory responses and insulin resistance. 2014 Apr 1 2
39 24682752 Sphingosine kinase-1 protects differentiated N2a cells against beta-amyloid25-35-induced neurotoxicity via the mitochondrial pathway. 2014 May 2
40 24759103 New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. 2014 May 30 2
41 25002116 Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. 2014 Oct 2
42 25460165 Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease. 2014 1
43 23011090 Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis. 2013 Oct 4
44 23328083 Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB. 2013 May 1
45 23359503 Usage of sphingosine kinase isoforms in mast cells is species and/or cell type determined. 2013 Mar 1 1
46 21765468 Defining a role for sphingosine kinase 1 in p53-dependent tumors. 2012 Mar 1 2
47 22668972 Proximal cerebral arteries develop myogenic responsiveness in heart failure via tumor necrosis factor-α-dependent activation of sphingosine-1-phosphate signaling. 2012 Jul 10 1
48 22707406 Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis. 2012 Aug 2
49 21245730 Isoflurane activates intestinal sphingosine kinase to protect against renal ischemia-reperfusion-induced liver and intestine injury. 2011 Feb 1
50 20053797 Isoflurane via TGF-beta1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules. 2010 Apr 1