Cholesterol

solute carrier family 10 member 2 ; Homo sapiens







30 Article(s)
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1 33189717 S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. 2021 Feb 1 2
2 34346218 Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity. 2021 Aug 25 2
3 32201314 Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges. 2020 Aug 1
4 31194565 Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2). 2019 Aug 5 2
5 29198943 Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers. 2018 Mar 2
6 29304731 Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial. 2018 Jan 5 4
7 30129377 Elobixibat, the first-in-class Ileal Bile Acid Transporter inhibitor, for the treatment of Chronic Idiopathic Constipation. 2018 Aug 1
8 28303230 A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides. 2017 Mar 2
9 28336180 An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT). 2017 Oct 6
10 25855079 N-glycosylation is essential for ileal ASBT function and protection against proteases. 2015 Jun 15 1
11 24317697 Structural basis of the alternating-access mechanism in a bile acid transporter. 2014 Jan 23 2
12 24498857 Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2). 2014 Apr 15 3
13 23678871 Discovery of a highly potent, nonabsorbable apical sodium-dependent bile acid transporter inhibitor (GSK2330672) for treatment of type 2 diabetes. 2013 Jun 27 2
14 23752471 Arylsulfonylamino-benzanilides as inhibitors of the apical sodium-dependent bile salt transporter (SLC10A2). 2013 Jun 10 1
15 23815591 Transmembrane domain V plays a stabilizing role in the function of human bile acid transporter SLC10A2. 2013 Jul 30 2
16 24045943 Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation. 2013 Nov 8 2
17 21646357 Transmembrane helix 1 contributes to substrate translocation and protein stability of bile acid transporter SLC10A2. 2011 Aug 5 2
18 21976025 Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT. 2011 Oct 5 1
19 18063707 Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. 2008 Feb 8
20 16484503 Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences. 2006 Sep 2
21 16541252 The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships. 2006 Mar 1
22 15604201 Cholesterol modulates human intestinal sodium-dependent bile acid transporter. 2005 May 5
23 16134950 Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1). 2005 Sep 8 1
24 15350125 Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2). 2004 Sep 14 3
25 12562847 Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB. 2003 May 2
26 12819193 Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. 2003 Sep 5 1
27 11808323 [Hypolipidemic drugs--ileal Na+/bile acid cotransporter inhibitors (S-8921 etc)]. 2002 Jan 2
28 12177176 Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94. 2002 Aug 1
29 12475240 Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor. 2002 Dec 17 1
30 9109432 Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). 1997 Apr 15 1