Hydrogen

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 35172577 Discovery of Anticancer Hybrid Molecules by Supervised Machine Learning Models and in Vitro Validation in Drug Resistant Chronic Myeloid Leukemia Cells. 2022 Feb 28 2
2 35470777 In silico design and computational evaluation of novel 2-arylaminopyrimidine-based compounds as potential multi-targeted protein kinase inhibitors: application for the native and mutant (T315I) Bcr-Abl tyrosine kinase. 2022 Apr 26 1
3 34508625 ABL1 and Cofilin1 promote T-cell acute lymphoblastic leukemia cell migration. 2021 Oct 12 1
4 32424388 Is breaking of a hydrogen bond enough to lead to drug resistance? 2020 Jun 18 1
5 27966954 Discovery of 4-Methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((1-nicotinoylpiperidin-4-yl)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding. 2017 Jan 12 1
6 28338290 Identification of natural inhibitors of Bcr-Abl for the treatment of chronic myeloid leukemia. 2017 Oct 1
7 23679864 Discovery of picomolar ABL kinase inhibitors equipotent for wild type and T315I mutant via structure-based de novo design. 2013 Jun 5 1
8 20072125 Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. 2010 Jan 28 1
9 20808434 Optimized hydrophobic interactions and hydrogen bonding at the target-ligand interface leads the pathways of drug-designing. 2010 Aug 16 1
10 19164531 Conformational disturbance in Abl kinase upon mutation and deregulation. 2009 Feb 3 1
11 8590002 The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct. 1995 Oct 15 1
12 1281542 Secondary structure of Src homology 2 domain of c-Abl by heteronuclear NMR spectroscopy in solution. 1992 Dec 15 1