Pub. Date : 2020 Jun 18
PMID : 32424388
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As an example, the crystal structure of the kinase inhibitor dasatinib bound to the Abl1 kinase shows a hydrogen bond between the drug and residue Thr315 and very few contacts between the drug and residues Val299 and Phe317, yet mutations in those residues lead to drug resistance. | Hydrogen | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |