Arginine

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







53 Article(s)
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1 33644712 The tyrosine kinase c-Abl potentiates interferon-mediated antiviral immunity by STAT1 phosphorylation. 2021 Feb 19 1
2 32240815 Arg mediates LPS-induced disruption of the pulmonary endothelial barrier. 2020 May - Jun 2
3 30861422 A tetrameric protein scaffold as a nano-carrier of antitumor peptides for cancer therapy. 2019 Jun 1
4 29463776 Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis. 2018 Feb 20 7
5 28368422 Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma. 2017 Aug 10 4
6 28386107 Constitutively active ABL family kinases, TEL/ABL and TEL/ARG, harbor distinct leukemogenic activities in vivo. 2017 Dec 1
7 28555614 Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases. 2017 May 30 6
8 25620702 c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit. 2015 Feb 3 1
9 25814671 Targeting Abl kinases to regulate vascular leak during sepsis and acute respiratory distress syndrome. 2015 May 4
10 25946048 Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility. 2015 1
11 24096484 c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer. 2014 Sep 4 4
12 24891505 Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin. 2014 Jul 11 8
13 23383209 Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1. 2013 3
14 21892207 c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression. 2012 Apr 5 1
15 22675626 Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics. 2012 1
16 22810897 Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1. 2012 Jul 17 1
17 23226579 Activation of abl family kinases in solid tumors. 2012 May 3
18 21417343 Crystal structures of ABL-related gene (ABL2) in complex with imatinib, tozasertib (VX-680), and a type I inhibitor of the triazole carbothioamide class. 2011 Apr 14 1
19 21602891 Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation. 2011 Nov 17 3
20 20110615 Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg. 2010 2
21 20150913 c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3. 2010 Aug 3
22 20737438 The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts. 2010 Oct 3
23 19679652 N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor. 2009 Oct 16 1
24 17700528 Aggressive breast cancer cells are dependent on activated Abl kinases for proliferation, anchorage-independent growth and survival. 2008 Feb 14 2
25 18827006 SHP-2 is a novel target of Abl kinases during cell proliferation. 2008 Oct 15 3
26 18945674 Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components. 2008 Dec 19 1
27 17211892 Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded. 2007 Apr 1 5
28 17306540 A critical role for cortactin phosphorylation by Abl-family kinases in PDGF-induced dorsal-wave formation. 2007 Mar 6 1
29 17686996 Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin. 2007 Oct 1
30 17892306 Use of a chemical genetic technique to identify myosin IIb as a substrate of the Abl-related gene (Arg) tyrosine kinase. 2007 Oct 16 2
31 16205964 Immunohistochemical analysis of platelet-derived growth factor receptor-alpha, -beta, c-kit, c-abl, and arg proteins in glioblastoma: possible implications for patient selection for imatinib mesylate therapy. 2006 Jan 2
32 16899465 c-Abl interacts with the WAVE2 signaling complex to induce membrane ruffling and cell spreading. 2006 Oct 20 1
33 15659545 The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. 2005 Feb 1 1
34 15735735 Ubiquitination and degradation of the Arg tyrosine kinase is regulated by oxidative stress. 2005 Apr 7 2
35 16151465 A single nucleotide polymorphism in the coding region of ABL and its effects on sensitivity to imatinib. 2005 Nov 1
36 14993293 Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. 2004 Mar 2
37 15039778 Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation. 2004 Mar 1
38 12569093 Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response. 2003 Apr 11 12
39 12748290 Two distinct phosphorylation pathways have additive effects on Abl family kinase activation. 2003 Jun 1
40 12775773 Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases. 2003 Jul 1 1
41 12777400 Catalase activity is regulated by c-Abl and Arg in the oxidative stress response. 2003 Aug 8 2
42 12080468 Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG. 2002 Jun 27 1
43 10706884 A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation. 2000 Mar 15 3
44 10763825 The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways. 2000 Mar 23 2
45 9828110 Increment of nonreceptor tyrosine kinase Arg RNA as evaluated by semiquantitative RT-PCR in granulocyte and macrophage-like differentiation of HL-60 cells. 1998 Nov 25 1
46 9211900 ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks. 1997 Jul 11 3
47 8637720 Analysis of chimeric Gag-Arg/Abl molecules indicates a distinct negative regulatory role for the Arg C-terminal domain. 1996 Feb 1 7
48 8700546 Subcellular localization of the Arg protein tyrosine kinase. 1996 Jul 4 1
49 7565714 Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions. 1995 Oct 1
50 8125961 Use of synthetic peptide libraries and phosphopeptide-selective mass spectrometry to probe protein kinase substrate specificity. 1994 Mar 11 1