| 1 |
22772060 | MK-0457, an Aurora kinase and BCR-ABL inhibitor, is active in patients with BCR-ABL T315I leukemia. | 2013 Jan |
3 |
| 2 |
23495751 | Comparing immobilized kinase inhibitors and covalent ATP probes for proteomic profiling of kinase expression and drug selectivity. | 2013 Apr 5 |
1 |
| 3 |
23556431 | Activity of histone deacetylase inhibitors and an Aurora kinase inhibitor in BCR-ABL-expressing leukemia cells: Combination of HDAC and Aurora inhibitors in BCR-ABL-expressing cells. | 2013 Apr 4 |
4 |
| 4 |
22521726 | Gadd45a transcriptional induction elicited by the Aurora kinase inhibitor MK-0457 in Bcr-Abl-expressing cells is driven by Oct-1 transcription factor. | 2012 Aug |
1 |
| 5 |
19874801 | Targets and effectors of the cellular response to aurora kinase inhibitor MK-0457 (VX-680) in imatinib sensitive and resistant chronic myelogenous leukemia. | 2010 Mar 1 |
3 |
| 6 |
20388735 | Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias. | 2010 May |
2 |
| 7 |
20563869 | Efficacy of MK-0457 and in combination with vorinostat against Philadelphia chromosome positive acute lymphoblastic leukemia cells. | 2010 Nov |
3 |
| 8 |
19338751 | Mechanism of MK-0457 efficacy against BCR-ABL positive leukemia cells. | 2009 Mar 20 |
2 |
| 9 |
19549414 | [Research progress on aurora kinase inhibitor MK-0457 in therapy for some hematological malignancies -- review]. | 2009 Jun |
2 |
| 10 |
18829489 | Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells. | 2008 Oct 1 |
2 |
| 11 |
16990603 | MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation. | 2007 Jan 15 |
1 |
| 12 |
17710227 | Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency. | 2007 Sep |
1 |
| 13 |
16046538 | Inhibition of drug-resistant mutants of ABL, KIT, and EGF receptor kinases. | 2005 Aug 2 |
1 |