Title : Mechanism of MK-0457 efficacy against BCR-ABL positive leukemia cells.

Pub. Date : 2009 Mar 20

PMID : 19338751






2 Functional Relationships(s)
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1 Mechanism of MK-0457 efficacy against BCR-ABL positive leukemia cells. VX680 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 These results indicate that MK-0457 is effective in CML cells by the down-regulation of HSPs which may relate to BCR-ABL stability, and offer new information regarding the molecular basis of strategy against to CML. VX680 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens